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首页> 外文期刊>International Journal of Research in Medical Sciences >Analysis of FNAC in diagnosis of lymphadenopathy-a retrospective study from a regional cancer centre, Cuttack, Odisha
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Analysis of FNAC in diagnosis of lymphadenopathy-a retrospective study from a regional cancer centre, Cuttack, Odisha

机译：淋巴结病的诊断中FNAC分析 - 区域癌症中心，鸡蹄癌的回顾性研究

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Background: Lymphadenopathy is one of the most common clinical presentations and major causes of morbidity. Thus, clinical recognition and urgent diagnosis is of paramount importance. So, we aimed to analysis the diagnostic role of fine needle aspiration cytology (FNAC) in superficial lymphadenopathy in a regional cancer centre, Odisha, India. Methods: A total 1129 cases were retrieved from the hospital record retrospectively from the patients who had presented with superficial lymphadenopathy from January 2015 to December 2015. Results: Out of 1129 lymphadenopathy cases, 671 (59.43%) were male and 458 (40.56%) were female with male to female ratio 1.46:1. The age of the patients ranged from 4 years to 83 years with mean age 48.57 years. The most common site was observed in cervical lymph node 493 (43.66%) followed by submandibuar lymph nodes 198 (17.53%) and supraclavicular lymph nodes 172 (15.23%). 584 (51.27%) were malignant and 545 (48.27%) were benign. Reactive hyperplasia was most common 318 (58.34%) among benign cases where as metastatic squamous cell carcinoma was the most common 261 (50.77%) among malignant lesions. By FNAC all benign lesions were correctly diagnosed, and primary sites of malignancy identified in 442 (85.59%) cases. Cyto-histo correlation was done in 399 cases. The overall diagnostic accuracy of FNAC was found to be 93.98%, sensitivity 93.88%, specificity 94.64%, positive predictive value 99.8% and negative predictive value 71.62%. Conclusions: FNAC is a highly sensitive and specific tool for early detecting primary malignancy and metastatic lesions. Many inflammatory lesions can be treated based on FNAC alone.
机译：背景：淋巴结病是最常见的临床演示和发病率的主要原因之一。因此，临床认识和紧急诊断至关重要。因此，我们旨在分析细针假性细胞学（FNAC）在地区癌症中心，奥西沙，印度的浅表淋巴结病中的诊断作用。方法：从2015年1月到2015年12月，从患有浅表淋巴结病的患者从医院记录中检索了1129例。结果：出于1129例淋巴结病病例，671例（59.43％）是男性，458名（40.56％）女性与女性比例为1.46：1。患者的年龄范围为4岁至83岁，平均年龄为48.57岁。在宫颈淋巴结493（43.66％）中观察到最常见的位点，其次是子宫颈淋巴结198（17.53％）和Suprachucular淋巴结172（15.23％）。 584（51.27％）是恶性的，545（48.27％）是良性的。反应性增生是最常见的318（58.34％）之间的良性病例，因为转移性鳞状细胞癌是恶性病变中最常见的261（50.77％）。通过FNAC，所有良性病变被正确诊断出来，并在442例（85.59％）案件中鉴定了恶性肿瘤的主要部位。 Cyton-histo相关是在399例中进行的。发现FNAC的整体诊断准确性为93.98％，灵敏度93.88％，特异性94.64％，阳性预测值99.8％，负预测值为71.62％。结论：FNAC是一种高度敏感和特异性的工具，可提前检测一次恶性恶性肿瘤和转移性病变。许多炎症病变可以仅基于单独的FNAc治疗。

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