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首页> 外文期刊>International Journal of Reproduction, Contraception, Obstetrics and Gynecology >Fibrinogen levels helps in early detection of abnormal pregnancies
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Fibrinogen levels helps in early detection of abnormal pregnancies

机译：纤维蛋白原水平有助于早期发现异常妊娠

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Background: Haemostatic failure as an end result of various complications of pregnancy is an important cause of maternal mortality in India. The main aim of this study is to detect the levels of fibrinogen in abnormal pregnancy i.e. Pregnancy induce hypertension (PIH), Intra uterine fetal death (IUFD), Missed abortion, Abruptio placenta. Methods: Study was conducted on 150 in patients joined in Obstetrics ward private hospital, Andhra Pradesh, 50 are control subjects and 100 are study patients, Out of hundred (100) cases, 40 are PIH, 25 are IUFD, 25 are Missed abortion, and 10 are Abruptio placentae. Estimated for fibrinogen, D-Dimer, total proteins, Albumin. Results: The fibrinogen levels in present study decreased significantly. PIH (Control mean 442.0, S.D ±43.38, Test mean 296.0, S.D ±48.03, p0.001). IUFD (Control mean 442.0, S.D±43.38, Test mean 262.4, S.D±20.06, p0.001). Missed abortion (Control mean 442.0, S.D ±43.38, Test mean 250.80, S.D±26.13, p0.001). Abruptio placentae (Control mean 442.0, S.D±43.38, Test mean 210.5, S.D±87.38, P0.001). D-dimer levels are estimated semi quantitatively and the levels were found to be increased. Total proteins and albumin are decreased in all the cases, but significantly in PIH (T.P-Control mean6.25, S.D±0.65, Test mean 5.25, S.D±1.57, p0.001, Albumin- Control mean 2.79, S.D±0.34, Test mean 2.23, S.D±0.59, p0.001). Conclusions: The estimation of plasma fibrinogen is helpful not only in the early diagnosis of haemostatic failure but also to guide replacement therapy during the fibrinopenic state.
机译：背景：血压失败作为怀孕各种并发症的最终结果是印度孕产妇死亡率的重要原因。本研究的主要目的是检测异常妊娠中纤维蛋白原的水平，即妊娠诱发高血压（PIH），子宫内胎儿死亡（IUFD），错过堕胎，突发胎盘。方法：研究在150岁的患者中进行，加入妇女私立医院，50例是对照科目，100是研究患者，占百分之百（100）例，40例是PIH，25例IUFD，25次缺少堕胎， 10是磨牙胎盘。估计纤维蛋白原，D-二聚体，总蛋白，白蛋白。结果：目前研究的纤维蛋白原水平显着下降。 PIH（控制平均442.0，S.D±43.38，测试平均296.0，S.D±48.03，P <0.001）。 IUFD（控制平均442.0，S.D±43.38，测试平均值262.4，S.D±20.06，P <0.001）。错过堕胎（控制平均442.0，S.D±43.38，测试平均250.80，S.D±26.13，P <0.001）。磨牙胎盘（控制平均442.0，S.D±43.38，测试平均值210.5，S.D±87.38，P <0.001）。 D-Dimer水平定量估计，并且发现水平增加。在所有情况下，总蛋白质和白蛋白减少，但PIH（TP-CONTROL均值6.25，SD±0.65，测试平均值5.25，SD±1.57，P <0.001，白蛋白控制平均值2.79，SD±0.34，测试平均2.23，SD±0.59，P <0.001）。结论：血浆纤维蛋白原的估计不仅有助于在血压衰竭的早期诊断中，还有助于在纤维蛋白稳态期间引导替代疗法。

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