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首页> 外文期刊>International Journal of Surgical Oncology >Prognostic Factors and Survival Time in Patients with Small Bowel Tumors: A Retrospective Observational Study
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Prognostic Factors and Survival Time in Patients with Small Bowel Tumors: A Retrospective Observational Study

机译：小肠肿瘤患者的预后因素和生存时间：回顾性观测研究

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This study examines survival time in patients with small bowel tumors and determines its contributing factors. In this retrospective analytical study, the medical records of 106 patients with small bowel cancer (from 2006 to 2011) were investigated. The patients’ data were extracted, including age, gender, clinical presentation, location of tumor, histological type, grade of tumor, site of metastasis, and type of treatment. The Kaplan-Meier test was used to estimate the overall survival time and the Log-rank test to compare the survival curves. The Cox regression was also used to evaluate the effect of the confounding variables on survival time. This study was conducted on 106 patients with a median age of 60 years (Min: 7, Max: 87). The tumor types included adenocarcinoma (n=78, 73.6%), MALToma (n=22, 20.8%), neuroendocrine tumors (n=4, 3.8%), and sarcoma (n=2. 1.8%). Grade 3 adenocarcinomas had a significantly lower survival time (HR: 1.48, 95% CI: 0.46-2.86; P=.001). Combined therapy (chemotherapy and surgery) vs. single-therapy (only surgery) had no significant effects on the survival of the patients with MALToma (5 vs. 3 months, 95% CI: 1.89-5.26; P=.06). There were no significant differences between the survival time in adenocarcinoma and MALToma (12 vs. 20 months, 95% CI: 6.24-24.76; P=.49). Tumor grade was the only independent prognostic factor that affected survival in adenocarcinoma. The patients diagnosed with MALToma in the study also had a poor prognosis, and the type of treatment had no significant effect on their survival.
机译：本研究检测小肠肿瘤患者的生存时间，并确定其贡献因素。在这项回顾性分析研究中，调查了106例小肠癌患者（从2006年到2011年）的病历。提取患者的数据，包括年龄，性别，临床介绍，肿瘤的位置，组织学型，肿瘤等级，转移遗址和治疗类型。 KAPLAN-MEIER测试用于估计整体生存时间和日志秩检验以比较生存曲线。 Cox回归还用于评估混淆变量对生存时间的影响。该研究是在106名中位60岁的患者进行的（MIN：7，MAX：87）。肿瘤类型包括腺癌（n = 78,73.6％），麦芽瘤（n = 22,20.8％），神经内分泌肿瘤（n = 4,3.8％）和肉瘤（n = 2。1.8％）。 3级腺癌的存活时间显着降低（HR：1.48,95％CI：0.46-2.86; p = .001）。联合治疗（化疗和手术）与单疗法（仅手术）对患有麦芽瘤患者的生存没有显着影响（5 vs.3个月，95％CI：1.89-5.26; p = .06）。在腺癌和麦芽瘤中生存时间之间没有显着差异（12 vs.20个月，95％CI：6.24-24.76; p = .49）。肿瘤等级是影响腺癌中生存的唯一独立的预后因素。在该研究中诊断出麦芽瘤的患者也具有较差的预后，治疗类型对其存活率没有显着影响。

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