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首页> 外文期刊>EFSA Journal >Re‐evaluation of sodium aluminium silicate (E?554) and potassium aluminium silicate (E?555) as food additives
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Re‐evaluation of sodium aluminium silicate (E?554) and potassium aluminium silicate (E?555) as food additives

机译：重新评估硅酸铝钠（E？554）和铝硅酸铝（E？555）作为食品添加剂

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The Panel on Food Additives and Flavourings (FAF) provided a scientific opinion re‐evaluating the safety of Sodium aluminium silicate (E 554) and potassium aluminium silicate (E 555) as food additives. The Scientific Committee for Food (SCF) assigned these food additives together with other aluminium‐containing food additives a provisional tolerable weekly intake (PTWI) of 7 mg aluminium/kg body weight (bw). In 2008, EFSA established a tolerable weekly intake (TWI) of 1 mg aluminium/kg bw per week. Sodium aluminium silicate was shown in rats to be absorbed to a limited extent at 0.12 ± 0.011%. The Panel considered that potassium aluminium silicate would be absorbed and become systemically available similarly to sodium aluminium silicate. No information on the physicochemical characterisation of sodium aluminium silicate and potassium aluminium silicate when used as food additives has been submitted and only very limited toxicological data were available for sodium aluminium silicate. Exposure to E 554 was calculated based on the reported use levels in food supplements. Exposure to aluminium from this use of E 554 was calculated to exceed the TWI for aluminium. Based on the data provided by interested business operators, the Panel considered that E 555 is not being used as a carrier, but as an inseparable component of ‘potassium aluminium silicate‐based pearlescent pigments’. The Panel calculated the regulatory maximum exposure to E 555 as a carrier for titanium dioxide (E 171) and iron oxides and hydroxides (E 172). Exposure to aluminium from this single use at the maximum permitted level could theoretically far exceed the TWI. Considering that only very limited toxicological data and insufficient information on the physicochemical characterisation of both food additives were available, the Panel concluded that the safety of sodium aluminium silicate (E 554) and potassium aluminium silicate (E 555) could not be assessed.
机译：该小组对食品添加剂和香料（FAF）提供了科学的观点重新评估硅酸铝钠的安全性（E 554）和硅酸铝钾（E 555）作为食品添加剂。所述食品科学委员会（SCF）具有7毫克铝/ kg体重（BW）其它含铝食品添加剂一个临时可忍受每周摄入量（PTWI）分配这些食品添加剂一起。在2008年，EFSA建立的1个毫克铝/ kg体重，每周可容忍的每周摄入量（TWI）。铝硅酸钠是在大鼠中显示在0.12±0.011％被吸收到一个有限的程度。小组认为硅酸铝钾会被吸收，成为全身可利用类似于铝硅酸钠。作为食品添加剂使用时，在铝硅酸钠和钾硅酸铝的物理化学表征没有信息已提交，只有非常有限的毒理学数据是可用的铝硅酸钠。根据食品添加剂的使用报告的水平计算曝光到E 554。计算从这个采用E 554的暴露于铝到超过铝的TWI。基于由感兴趣的经营者提供的数据，小组认为Ë555不被用作载体，但作为“铝钾硅酸盐系珠光颜料”不可分割的组成部分。小组计算出的调节的最大暴露到E 555作为用于二氧化钛的载体（E 171）和铁氧化物和氢氧化物（E 172）。暴露于铝从在最大在这次使用允许电平理论上可以远远超过TWI。考虑到只有非常有限的毒理学数据和在两个食品添加剂的物理化学表征不足信息是可利用的，小组的结论是硅酸铝钠（E 554）和氢硅酸铝（E 555）的安全性无法评估。

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