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首页> 外文期刊>Endoscopy International Open >Safety and efficacy of digital single-operator pancreatoscopy for obstructing pancreatic ductal stones
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Safety and efficacy of digital single-operator pancreatoscopy for obstructing pancreatic ductal stones

机译：数字单次运算符胰蛋白镜检查阻塞胰腺导管石材的安全性和有效性

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Background and study aims?The role of the digital single-operator pancreatoscopy (D-SOP) with electrohydraulic (EHL) or laser lithotripsy (LL) in treating pancreatic ductal stones is unclear. We investigated the safety and efficacy of D-SOP with EHL or LL in patients with obstructing pancreatic duct stones. Patients and methods?Retrospective analysis of 109 patients who underwent D-SOP for pancreatic stones at 17 tertiary centers in the United States and Europe from February 2015 to September 2017. Logistic regression was performed to identify factors associated with the need for more than one D-SOP with EHL/LL. Results?Most patients were males (70.6?%),mean age 54.7 years. Fifty-nine (54.1?%) underwent EHL and 50 (45.9?%) underwent LL. Mean procedure time was longer in the EHL group (74.4?min vs 53.8 min; P??0.001). Ducts were completely cleared (technical success) in 89.9?% of patients (94.1?% in EHL vs 100?% in LL; P?=?0.243), achieved in a single session in 73.5?% of patients (77.1?% by EHL and 70?% by LL; P=?0.5).D-SOP failed in 11 patients (10.1?%); 6 patients were treated with extracorporeal shockwave lithotripsy (ESWL), 1 with surgery,1 with combined treatment (ESWL?+?D-SOP EHL) and 3 with other. Fourteen adverse events occurred in 11 patients (10.1?%). Patients with more than three ductal stones were more likely to have technical failure compared to those with less than three stones (17?% vs. 4.8?%; P?=?0.04). Having more than three stones was independently associated with the need for more than one D-SOC EHL/LL session (OR 2.94, 95?% CI 1.13?–?7.65). Conclusion?D-SOP with EHL or LL is effective and safe in patients with pancreatic ductal stones.
机译：背景和研究旨在？数字单次操作员胰犬镜检查（D-SOP）与电液（EHL）或激光碎石术（LL）治疗胰腺导管石块的作用尚不清楚。我们调查了D-SOP与胰腺导管结石患者的EHL或LL的安全性和有效性。患者及方法？2015年2月至2017年2月在美国和欧洲17岁的三级中心接受了D-SOP胰腺D-SOP患者的回顾性分析。签署了物流回归，以确定与多个D.相关的因素-sop与ehl / ll。结果？大多数患者是男性（70.6？％），平均54.7岁。五十九（54.1〜％）接受EHL和50（45.9倍）接受了LL。 EHL组的平均程序时间更长（74.4？min 53.8 min; p？<0.001）。导管在89.9？％患者中完全清除（技术成功）（EHL中的94.1〜100℃，LL的100μl％，P？= 0.243），在73.5岁的单一会议中达到73.5％（77.1〜％ ehl和70？％by ll; p =？0.5）.D-SOP在11名患者中失败（10.1？％）; 6名患者用体外冲击波型碎石（ESWL），1，手术治疗，1，1含有组合治疗（ESWL？+→D-SOP EHL）和3种。 11名患者发生了十四个不良事件（10.1？％）。与具有少于三块石头的人相比，患有三个以上的导管石块的患者更可能具有技术失效（17℃，vs.4.8≤4.8≤4.8？p？= 0.04）。具有三个以上的石头与多于一个D-SOC EHL / LL会话（或2.94,95？％CI 1.13）的需要独立相关联。结论？D-SOP具有EHL或LL的胰腺导管患者是有效和安全的。

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