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首页> 外文期刊>Endoscopy International Open >Fine-needle biopsy is superior to fine-needle aspiration of suspected gastrointestinal stromal tumors: a large multicenter study
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Fine-needle biopsy is superior to fine-needle aspiration of suspected gastrointestinal stromal tumors: a large multicenter study

机译：细针活检优于疑似胃肠肿瘤的微针抱负：大型研究

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Background and study aims?There are numerous studies published on the diagnostic yield of the new fine-needle biopsy (FNB) needles in pancreas masses. However, there are limited studies in suspected gastrointestinal stromal tumors (GIST lesions). The aim of this study was to evaluate the diagnostic yield of a new fork-tip FNB needle. Patients and methods?This was a multicenter retrospective study of consecutive patients from prospectively maintained databases comparing endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) versus endoscopic ultrasound-guided FNB (EUS-FNB) using the fork-tip needle. Outcomes measured were cytopathology yield (ability to obtain tissue for analysis of cytology), ability to analyze the tissue for immunohistochemistry (IHC yield), and diagnostic yield (ability to provide a definitive diagnosis). Results?A total of 147 patients were included in the study of which 101 underwent EUS-FNB and 46 patients underwent EUS-FNA. Median lesion size in each group was similar (21?mm vs 25?mm, P?=?0.25). Cytopathology yield, IHC yield, and diagnostic yield were 92?% vs 46?% (P?=?0.001), 89?% vs 41?% (P?=?0.001), and 89?% vs 37?% (P?=?0.001) between the FNB and FNA groups, respectively. Median number of passes was the same between the two groups at 3.5. Conclusion?EUS-FNB is superior to EUS-FNA for diagnostic yield of suspected GIST lesions. This should be confirmed with a prospective study.
机译：背景和学习目标？在胰腺肿块中新细针活检（FNB）针的诊断产量发表了许多研究。然而，在疑似胃肠肿瘤（GIST病变）中存在有限的研究。本研究的目的是评估新的叉尖FNB针的诊断产量。患者和方法？这是一项多中心回顾性研究，从前瞻性地维持数据库比较内窥镜超声引导的微针吸入（EUS-FNA）与内窥镜超声引导的FNB（EUS-FNB）使用叉尖针进行了比较。测量的结果是缩细胞病理产量（能够获得用于分析细胞学的组织），分析免疫组织化学（IHC产量）和诊断产率的组织（提供明确诊断的能力）。结果？在研究中，共有147名患者纳入其中101例eUS-FNB和46名患者接受了EUS-FNA。每个组中的中位数病变大小相似（21？mm与25？mm，p？= 0.25）。细胞病变产量，IHC产量和诊断产率为92〜46〜46？％（P？= 0.001），89？％Vs 41？％（P？= 0.001），89〜％Vs 37？％（P分别在FNB和FNA基团之间分别在FNB和FNA基团之间进行。在3.5时，两组之间的中位数在两组之间是相同的。结论？EUS-FNB优于EUS-FNA，用于诊断疑似的主体病变。这应该通过前瞻性研究确认。

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