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Cap-fitted endoscopic mucosal resection of ≥?20?mm colon flat lesions followed by argon plasma coagulation results in a low adenoma recurrence rate

机译:盖子内窥镜粘膜切除≥2mmmmmma粘滞扁平病变,然后是氩等离子体凝固导致低腺瘤复发率

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Background and study aims?Endoscopic mucosal resection (EMR) is increasingly used for the treatment of large colonic polyps (≥?20?mm). A drawback of EMR is local adenoma recurrence. Therefore, we studied the impact of argon plasma coagulation (APC) of the EMR edge on local adenoma recurrence. Patients and methods?This was a retrospective study of patients with laterally spreading tumors (LST) ≥?20?mm, who underwent EMR from January 2009 to August 2018 and follow-up endoscopic assessment. A cap-fitted endoscope was used to assess completeness of resection by systematically inspecting the EMR defect for any macroscopic disease. This was followed by forced APC of the resection edge followed by clip closure of the defect. Surveillance colonoscopy was performed at 6 months after resection to detect recurrence. Results?Two hundred forty-six patients met the inclusion criteria. Most were female (53?%) and white (80?%), with a Median age of 64 years. Median polyp size was 35?mm (interquartile range, 30–45?mm). Most polyps were located in the right colon (77?%) and were removed by piecemeal EMR (70?%). Eleven patients (5?%) had residual tumor at the resection site. Conclusions?We observed low adenoma recurrence after argon plasma coagulation of the EMR edge with a cap fitted colonoscope in patients with LST ≥?20?mm of the colon, which requires further validation in a randomized controlled study.
机译:背景和研究旨在?内镜粘膜切除(EMR)越来越多地用于治疗大肠炎息肉(≥≤20Ωmm)。 EMR的缺点是局部腺瘤复发。因此,我们研究了EMR边缘对局部腺瘤复发的氩等离子体凝血(APC)的影响。患者和方法?这是对横向扩散肿瘤患者(LST)≥2mm的患者的回顾性研究,他从2009年1月到2018年1月至2018年8月和后续内窥镜评估。通过系统地检测任何宏观疾病的EMR缺陷,用于评估切除的完整性内窥镜。接下来是切除边缘的强制APC,然后夹住缺陷。在切除后6个月进行监测结肠镜检查以检测复发。结果?二百四十六名患者达到了纳入标准。大多数是女性(53?%)和白色(80?%),中位年龄为64岁。中位数息肉尺寸为35?mm(四分位数范围,30-45?mm)。大多数息肉位于右上结肠(77〜%),并通过零碎的EMR(70μm)除去。 11名患者(5?%)在切除部位有残留的肿瘤。结论?我们观察到EMR边缘氩血浆凝血后的低腺瘤复发与LST≥≤20Ω·20?毫米的患者的帽子粘连镜,这需要进一步验证随机对照研究。

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