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首页> 外文期刊>Endoscopy International Open >Lumen-apposing metal stents versus biliary fully-covered metal stents for EUS-guided drainage of pancreatic fluid collections: a case control study
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Lumen-apposing metal stents versus biliary fully-covered metal stents for EUS-guided drainage of pancreatic fluid collections: a case control study

机译：腔藏金属支架与胆道完全覆盖的金属支架，用于胰酸液系列的令人调心的引导排水：案例控制研究

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Background and study aims?Endoscopic ultrasound (EUS)-guided drainage has become first-line treatment for pancreatic fluid collections (PFC). The aim of this study was to compare the effectiveness and safety of biliary fully-covered self-expandable metal stents (BFCSEMS) and lumen-apposing metal stents with electrocautery (EC-LAMS). Patients and methods?From April 2008 to March 2017, consecutive patients with symptomatic PFC drained under EUS-guidance with metal stents were included. Patients drained with EC-LAMS were considered the study group and those drained with BFCSEMS the control group.?Two primary endpoints were evaluated: effectiveness (defined as reduction of?≥?50?% of PFC size in cross-sectional imaging and improvement of symptoms 6 months after the transmural drainage) and safety. Results?Thirty patients were drained with EC-LAMS and 60 patients with BFCSEMS.?Patients and PFC baseline characteristics in both groups were similar. Use of a coaxial double pigtail plastic stent and a nasocystic lavage catheter was significantly less frequent in patients drained with EC-LAMS (33?% vs. 100?%, and 13?% vs. 58?%, respectively; P??0.0001). Technical success was 100?% in both groups. Procedure time was??30 minutes in all patients drained with EC-LAMS and over 30 minutes in all patients drained with BFCSEMS (P?=?0.0001). Clinical success was higher with a tendency to significance in patients drained with EC-LAMS (96?% vs. 82?%, P?=?0.055) and the adverse event rate was lower (4?% vs. 18?%, P?=?0.04). No case of procedure-related mortality was recorded. Conclusions?EC-LAMS and BFCSEMS are both effective for EUS-guided drainage of PFC. However, EC-LAMS requires less time to be performed and appears to be safer.
机译：背景和研究旨在？内窥镜超声（EUS）导射已成为胰液收集的一线治疗（PFC）。本研究的目的是比较胆道全覆盖的自膨胀金属支架（BFCSEM）和腔藏金属支架的有效性和安全性与电陶器（EC-LAMS）。患者和方法？从2008年4月到2017年3月，包括在与金属支架的EUS-Gugce下排出的症状PFC的连续患者。用EC-LAMs排出的患者被认为是研究组，并用BFCSEMS排出的那些对照组。评估了源终点：有效性（定义为横截面成像中的PFC尺寸的Δ≥≤50？50？％迁移排水后6个月的症状）和安全。结果？用EC-LAMS和60例BFCSEM患者排出30名患者。同类患者和PFC基线特征是相似的。使用同轴双尾塑料支架和鼻咽精灌洗导管在用EC-LAMS排出的患者中，分别在患者中缺乏频繁的频率显着较低（33〜100μm，分别为13倍，58μm≤％; P？<？ 0.0001）。两组的技术成功为100？％。术语时间是？<？30分钟的所有患者用EC-LAMS排干，并且在所有与BFCSEM中排出的患者中超过30分钟（P？= 0.0001）。临床成功较高，随着EC-LAMS排出的患者（96〜％vs.82？％，p？= 0.055）和不良事件率较低（4〜％，P.％，p ？=？0.04）。没有记录与程序相关的死亡率。结论？EC-LAMS和BFCSEMs对PFC引导引导的速度引导。然而，EC-LAMS需要更少的时间进行且似乎更安全。

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