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Dye-based chromoendoscopy following polypectomy reduces incomplete polyp resection

机译:染料的染色体镜检查术后胶乳切除术减少了不完全息肉切除

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Background and study aims?The completeness of a polyp resection is an important determinant of quality in colonoscopy, and may reduce incidence of interval cancers. Incomplete resection rates (IRR) vary widely and range from 6.5?% to 22.7?%. Residual disease is more likely with larger polyps, for sessile serrated adenomas, and with more proximal lesions. Chromoendoscopy is increasingly employed in lesion detection. The aims of this study were to assess local IRR, and to determine whether chromoendoscopy could correctly identify residual disease post polypectomy. Patients and methods?This was a prospective study examining post polypectomy sites. Chromoendoscopy (0.13?% indigo carmine) was applied to resection bases to identify residual disease. Targeted base biopsies were taken from identified residual disease (positive group) or random base biopsies were taken when a clear base was visualised (negative group). Overall rates of incomplete resection were documented. Reported rates post chromoendoscopy and actual histological rates were documented and compared. Results?A total of 102 polyps were identified for inclusion, of which 15?% (n?=?16) were excluded. Resection quality was evaluated in 86 polyps of 61 patients (female n?=?33 54?%; mean Age 62.3 years). Polyps were mainly removed by cold snare (n?=?71, 82.5?%). Most polyps (n?=?58, 67?%) measured between 5 to 10?mm. Polyps were largely located in the right colon (n?=?57, 66?%). Overall histological residual disease occurred in 17?/86 (19.6?%). Chromoendoscopy correctly identified residual disease in 13 of 17 bases (76.5?%). Only four of /86 (4.6?%) of polyp bases were missclassified post-chromoendoscopy (odds ratio 0.284 (95?% CI 0.0857–0.9409), P?=?0.03). Conclusion?Indigo carmine chromoendoscopy improves early detection of residual disease post polypectomy, reducing incomplete resection rates.
机译:背景和研究旨在?息肉切除的完整性是结肠镜检查中的质量的重要决定因素,可能降低间隔癌的发生率。切除率(IRR)的不完全差异很大,范围为6.5?%至22.7?%。残留疾病更可能具有较大的息肉,对于无梗塞的腺瘤,并且具有更多近端病变。衰退检测越来越多地使用微透视检查。本研究的目的是评估局部IRR,并确定复古镜检查是否可以正确识别残留疾病后患者患者。患者和方法?这是一项潜在的研究检查后蛋白切除术部位。综合镜检查(0.13〜%indigo carmine)用于切除碱以鉴定残留疾病。靶向碱度活组织检查是从鉴定的残留疾病(阳性群)或随机碱活检时,当明确碱被视为(阴性组)时。记录了不完全切除的总体税率。报告的速率后术后和实际的组织学率被记录并进行比较。结果?鉴定了总共102个息肉以包含,其中排除了15〜%(n?=Δ16)。在86名患者的86个息肉中评估切除质量(雌性N?=?33 54?%;平均年龄62.3岁)。息肉主要由冷圈护理除去(n?= 71,82.5?%)。大多数息肉(n?=Δ58,67?%)在5到10. mm之间测量。息肉在很大程度上位于右上的结肠(n?=Δ57,66?%)。总体组织学残留疾病发生在17〜86(19.6?%)。微型镜检查在17个碱基(76.5μl%)中正确鉴定了残留疾病。只有四个/ 86(4.6%)的息肉碱碱被灭菌后透视检查(差距为0.284(95〜%CI 0.0857-0.9409),p?= 0.03)。结论?Indigo Carmine综合镜检查提高了残留疾病蛋白切除术后的早期检测,降低了不完全切除率。

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