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首页> 外文期刊>Endoscopy International Open >Complete closure versus simple closure for perforations during colorectal endoscopic submucosal dissection
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Complete closure versus simple closure for perforations during colorectal endoscopic submucosal dissection

机译：完全闭合与结肠直肠内镜粘膜颌面粘膜粘膜下穿孔的简单闭合

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Background and study aims?The efficacy of complete closure versus simple closure for perforations during endoscopic submucosal dissection (ESD) has never been evaluated. We evaluated the efficacy of complete closure and simple closure for perforations and muscular layer injuries incurred during ESD. Patients and methods?Thirty-four consecutive patients who underwent “complete closure” or “simple closure” for correction of perforations and muscular layer injuries during colorectal ESD were enrolled in this study. Complete closure was performed by the mucosa-submucosa clip closure method using only conventional endo-clips. For simple closure, endo-clips are placed just for perforation or muscular layer injury, while leaving any mucosal defects open. Results?Among the 15 patients in the complete closure group, eight developed perforations and seven developed muscular layer injuries. Among the 19 patients in the simple closure group, six developed perforations and 13 developed muscular layer injuries during the ESD procedure. There were no statistically significant differences between the two groups in inflammatory reactions, adverse events, or length of the hospital stay. Conclusion?Complete closure and simple closure for perforations and muscular layer injuries during ESD seem to have similar efficacy. While simple closure for a perforation during ESD seems sufficient, further study will be required to confirm our results.
机译：背景和学习目标？从未评估了内窥镜粘膜下粘膜粘膜粘膜粘膜（ESD）期间穿孔的完全闭合与简单闭合的功效。我们评估了完全闭合和简单闭合在ESD期间发生的肌肉层损伤的疗效。患者和方法？在本研究中注册了在本研究中进行了用于校正穿孔和肌肉层损伤的“完全闭合”或“简单闭合”的三十四名患者。通过仅使用常规的内部夹子，通过粘液粘膜夹夹闭合方法进行完全闭合。对于简单的闭合，终点夹仅用于穿孔或肌肉层损伤，同时留下任何粘膜缺陷。结果？在完整的闭合组15名患者中，八个开发的穿孔和七层肌肉层损伤。在简单的闭合组19名患者中，六个发达的穿孔和13个在ESD程序期间发达的肌肉层损伤。两组在炎症反应，不良事件或住院时间长度之间没有统计学意义。结论？ESD期间穿孔和肌肉层损伤的完全闭合和简单闭合似乎具有相似的疗效。虽然ESD期间的穿孔简单闭合似乎足够了，但需要进一步研究来确认我们的结果。

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