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首页> 外文期刊>Endoscopy International Open >Small bowel angioectasia as a marker of frailty and poor prognosis
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Small bowel angioectasia as a marker of frailty and poor prognosis

机译：小肠血管学障碍作为脆弱性和预后差的标记

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Background and study aims?This study aimed to establish 5-year survival of patients diagnosed with bleeding small bowel (SB) angioectasia, with the hypothesis that many will suffer deaths relating to comorbidity rather than gastrointestinaI bleeding. Patients and methods?SB capsule endoscopy (SBCE) procedures, performed for suspected SB bleeding or iron deficiency anemia, with angioectasia isolated as the cause of SB bleeding and at least 5 years of follow-up data were isolated (n?=?125) along with an age-matched group with “normal” SBCE procedures (n?=?125). These were retrospectively analysed with further information on mortality and comorbidity gathered through hospital records. Results?Those with angioectasia had a median age of 72.7 years and comorbidities were common. The 5-year survival was 64.0?% (80/125) compared to 70.4?% (88/125) in those with “normal” SBCE. Those with significant cardiac or vascular comorbidity had a poorer survival (52.9?% (37/70) at 5 years) but anticoagulation/antiplatelets/ number of lesions or requirement endoscopic treatment seemed to make little difference. In those with SB bleeding secondary to angioectasia none of the subsequent deaths were directly attributable to gastrointestinal bleeding. Conclusions?In this cohort, SB angioectasia did not lead to any deaths but the 5-year survival was poor due to those diagnosed often being older and having comorbidities. This would support the hypothesis that a diagnosis of SB bleeding secondary to angioectasia suggests frailty.
机译：背景和学习症状？本研究旨在建立患者诊断出血肠（Sb）血管梭的患者的5年生存率，其中许多人会遭受与合并症有关的死亡，而不是胃肠道出血。患者和方法？SB胶囊内窥镜检查（SBCE）程序，用于疑似SB出血或缺铁性贫血，孤立的血管外形血栓分离为SB出血和至少5年的后续数据（n？= 125）随着年龄匹配的群体，具有“正常”的SBCE程序（n？= 125）。这些回顾性地分析了通过医院记录收集的死亡率和合并症的进一步信息。结果？那些血管学梭中的人数为72.7岁，常见的是。 5年期存活率为64.0？％（80/125），而“正常”SBCE的70.4％（88/125）。具有重要心脏或血管合并症的人的存活率较差（52.9？％（37/70），但抗凝/抗血液或病变或需求内窥镜治疗似乎几乎没有差异。在那些SB出血中，继发于血管外关节障碍，随后的死亡均未直接归因于胃肠道出血。结论？在这种队列中，Sb血管障碍不会导致任何死亡，但由于诊断术语常龄和具有合并症的人，5年的存活率差。这将支持对血管学梭中的Sb出血的诊断表明脆弱的假设表明脆弱。

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