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Effects of unrestricted access to flash glucose monitoring in type 1 diabetes

机译:不受限制的糖尿病闪光葡萄糖监测的影响

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Aims We assessed adherence and long‐term effects on HbA1c of unrestricted access to flash glucose monitoring (FGM) in a single diabetes centre. Methods In this observational study, we reviewed data files for all 411 patients with type 1 diabetes attending our clinic during a 2‐year period. Adherence was reported in those who initiated FGM in our clinic (n?=?321). Baseline and final HbA1c were noted for patients who continued FGM for more than 6?months without clinical conditions or interventions at baseline that could interfere with the effect of FGM on glycaemic control (n?=?270). Results After 2?years, the fraction of patients using FGM increased from 3% to 72%. Adherence to FGM was 88%. Baseline and final HbA1c was median (interquartile range) 63?mmol/mol (56, 74) (7.9% (7.3, 8.9)) and 59?mmol/mol (53, 68) (7.6% (7.0, 8.4)), respectively. The estimated difference final‐baseline HbA1c was ?4?mmol/mol (95% CI ?5, ?3) (?0.4% (?0.5, ?0.3)) ( P ?.001). No significant difference was seen for patients with baseline HbA1c?≤?7% (53?mmol/mol). The interval from initiation of FGM to final HbA1c was median 562?days (IQR 417, 662). The number of scans/day was median 11 (IQR 8, 13) and correlated negatively with both final and baseline HbA1c but not with change in HbA1c. Conclusions Following the introduction of unlimited access, nearly three quarters of the patients were FGM users. Long‐term adherence was good, and HbA1c improved in all patients except in those with optimal glycaemic control at baseline.
机译:目的是我们评估了对单一糖尿病中心的闪光葡萄糖监测(FGM)的无限期访问HBA1C的依从性和长期影响。方法在该观察性研究中,我们在2年期间审查了所有411名患有1型糖尿病患者的数据文件。在我们的诊所发起FGM的人中报告了遵守(n?= 321)。对于持续的FGM持续超过6?没有临床条件或在基线的干预患者可能干扰FGM对血糖控制的影响(n?= 270)的基线的干预患者,注意到基线和最终的HBA1c结果2岁以下,使用FGM的患者的一部分从3%增加到72%。对FGM的依恋为88%。基线和最终HBA1c是中值(四分位数范围)63?mmol / mol(56,74)(7.9%(7.3,8.9))和59?mmol / mol(53,68)(7.6%(7.0,8.4)),分别。估计的差异最终基线HBA1C是α4?mmol / mol(95%CI→5,α3)(α0.4%(Δ0.5,β0.3))(P <α.001)。对于基线HBA1C的患者没有看到显着差异?≤α7%(53μmol/ mol)。从FGM启动到最终HBA1C的间隔是中值562?天(IQR 417,662)。扫描/日的数量是11(IQR 8,13)的中位数11(IQR 8,13),并与最终和基线HBA1C负相关,但不随HBA1c的变化。结论在引入无限通道后,近四分之三的患者是FGM用户。长期粘附性很好,除了基线最佳血糖控制的患者外,HBA1C的改善。

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