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Advanced Effect of Moringa oleifera Bioconversion by Rhizopus oligosporus on the Treatment of Atopic Dermatitis: Preliminary Study

机译:辣木oleifera生物转化的先进效果洛杉矶寡孢菌对特应性皮炎的治疗方法:初步研究

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This study was conducted to determine if topical application of Moringa oleifera extracts and its bioconversion product fermented by Rhizopus oligosporus has therapeutic properties enhancement for treatment of atopic dermatitis. Rhizopus oligosporus (KCCM 11232P) was used to ferment Moringa leaves’ extracts in this study. Comparison of organic acids and flavonols in Moringa simple extracts and their fermented product by HPLC analysis revealed that concentration of organic acids and flavonols of bioconversion product was lower than that of hot water extracts. The fermentation process is used as a nutrient for isolation of each component by microorganisms and growth of microorganisms. The results demonstrated that MF extracts effectively reduced clinical features based on macrography, scratching count, and severity scores, as well as model’s serum IgE level, including histopathological analyses.
机译:进行了该研究以确定辣木oleifera提取物的局部应用及其发酵的Rhizopus oligosporus的生物转化产品是否具有治疗特性皮炎的治疗性能。 Rhizopus Oligosporus(KCCM 11232P)用于在本研究中发酵Moringa叶子的提取物。通过HPLC分析对辣木中的有机酸和黄酮醇的比较及其发酵产物显示,生物转化产物的有机酸和黄酮酚的浓度低于热水提取物的浓度。发酵过程用作通过微生物和微生物生长分离每个组分的营养素。结果表明,MF提取基于宏观,划伤计数和严重程度以及模型的血清IgE水平,有效地降低了临床特征,包括组织病理学分析。

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