...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Evidence-based complementary and alternative medicine: eCAM >Efficacy and Safety of Bushenjiangya-Optimized Granule for Left Ventricular Diastolic Dysfunction in Hypertensive Patients: A Double-Blind, Randomized, Placebo-Controlled Trial
【24h】

Efficacy and Safety of Bushenjiangya-Optimized Granule for Left Ventricular Diastolic Dysfunction in Hypertensive Patients: A Double-Blind, Randomized, Placebo-Controlled Trial

机译：Bushenjiangya优化颗粒在高血压患者左心室舒张功能障碍的疗效和安全性：双盲，随机，安慰剂对照试验

获取原文
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective. The study aimed to evaluate the efficacy and safety of Bushenjiangya-optimized (BSJYO) granule on left ventricular diastolic dysfunction (LVDD) in hypertensive (HTN) patients. Methods. 120 patients diagnosed with HTN plus LVDD were randomly assigned to the BSJYO granule group and placebo group, and all patients received basal western medicine (WM) treatment. After eight weeks of treatment, we evaluated echocardiography, traditional Chinese medicine (TCM) syndromes, 24-hour ambulatory blood pressure, liver and kidney functions, and adverse events. Major adverse cardiovascular events (MACEs) were collected at 6-month follow-up. Results. Compared with pretreatment, E/Ea (Doppler-derived index of filling pressure and worsening LVDD) significantly decreased significantly after 8 weeks of treatment in the BSJYO granule plus basal WM group (10.52?±?1.87 vs. 9.49?±?1.49, P0.01), alongside reductions in significantly effective response (SER), effective response (ER), and total effective response (TER?=?SER?+?ER) in TCM symptom scores (21.59% vs. 71.70%, P0.01). There were no differences between treatment groups in kidney and liver function, early adverse events, or MACE. Conclusion. BSJYO granule plus basal WM is an effective and safe therapy for HTN patients with LVDD.
机译：客观的。该研究旨在评估Bushengjiangya优化（Bsjyo）颗粒对高血压（HTN）患者左心室舒张功能障碍（LVDD）的疗效和安全性。方法。将120名诊断患有HTN Plus LVDD的患者随机分配给BSJyo颗粒组和安慰剂组，所有患者均接受基础西药（WM）治疗。经过八周的治疗后，我们评估了超声心动图，中医（中医）综合征，24小时动态血压，肝肾功能，以及不良事件。在6个月的随访中收集了主要的不良心血管事件（训练）。结果。与预处理相比，在BSJyo颗粒加基础WM组（10.52Ω·±1.87±1.87±1.87±0.39.79，P.±1.49，P <0.01），在中医症状评分中，在显着有效的响应（SER），有效响应（ER），有效响应（ER）和总有效响应（TERα=Δ+→ΔER）中的含量显着效应（SER）和总有效响应（21.59％，P <0.01 ）。肾脏和肝功能，早期不良事件或狼人之间的治疗组之间没有差异。结论。 Bsjyo颗粒加基础WM是对LVDD的HTN患者有效和安全的治疗。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号