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首页> 外文期刊>Gut and Liver >Detecting Early Pancreatic Cancer: Current Problems and Future Prospects
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Detecting Early Pancreatic Cancer: Current Problems and Future Prospects

机译：检测早期胰腺癌：当前问题和未来的前景

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The number of patients with pancreatic cancer (PC) is currently increasing in both Korea and Japan. The 5-year survival rate of patients with PC 13.0%; however, resection with minimal invasion (tumor size: ≤10 mm) increases the 5-year survival rate to 80%. For this reason, early detection is essential, but most patients with early-stage PC are asymptomatic. Early detection of PC has been reported to require screening of high-risk individuals (HRIs), such as those with a family history of PC, inherited cancer syndromes, intraductal papillary mucinous neoplasm, or chronic pancreatitis. Studies on screening of these HRIs have confirmed a significantly better prognosis among patients with PC who were screened than for patients with PC who were not screened. However, to date in Japan, most patients with early-stage PC diagnosed in routine clinics were not diagnosed during annual health checks or by surveillance; rather, PC was detected in these patients by incidental findings during examinations for other diseases. We need to increase the precision of the PC screening and diagnostic processes by introducing new technologies, and we need to pay greater attention to incidental clinical findings.
机译：韩国和日本胰腺癌（PC）的患者数量正在增加。 PC患者的5年生存率为13.0％;但是，以最小的侵袭（肿瘤大小：≤10mm）切除，将5年的存活率增加到80％。因此，早期检测至关重要，但大多数早期PC的患者无症状。据报道，PC的早期检测需要筛查高危个体（HRIS），例如具有PC家族历史的人，遗传癌症综合征，内科乳头状乳糜瘤或慢性胰腺炎。关于这些HRI的筛查的研究证实了筛选的PC患者的明显预后，而不是没有筛选的PC患者。但是，迄今为止日本，大多数患有在年度卫生检查期间诊断常规诊断的早期PC的患者均未诊断出来或监督;相反，在对其他疾病的考试期间，在这些患者中检测到PC。我们需要通过引入新技术来提高PC筛选和诊断过程的精度，我们需要更加注重偶然临床发现。

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