Double-blind, parallel group, placebo-controlled study of Kjellmaniella crassifolia Miyabe (Gagome) in human: The potential of Gagome to activate the immune system

Jun Nishihira; Mie Nishimura; Miwako Sugawara; Masafumi Kudo

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Double-blind, parallel group, placebo-controlled study of Kjellmaniella crassifolia Miyabe (Gagome) in human: The potential of Gagome to activate the immune system

机译：双盲，平行组，Kjellmaniella Crassifolia Miyabe（Gagome）的安慰剂对照研究人类：露头激活免疫系统的潜力

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Background: Marine brown algae, Kjellmaniella crassifolia Miyabe (Gagome) is extensively harvested in Northern Japan and is known to help improve the immune system and prevent lifestyle diseases by its functional constituents, particularly the polysaccharide fucoidan. However, since most scientific findings come from animal studies, we examined its potential effectiveness in humans to raise immune functions, using small amounts of Gagome to avoid overconsumption of iodide.

机译：背景：海洋褐藻，Kjellmaniella Crassifolia Miyabe（Gagome）在日本北部广泛收获，众所周知，通过其功能成分，特别是多糖Fucoinean来改善免疫系统并防止生活方式疾病。然而，由于大多数科学的结果来自动物研究，我们检查了人类潜在的有效性，以利用少量门廊来提高免疫功能，以避免过度发布碘化物。

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《Functional Foods In Health And Disease》 |2017年第10期|共15页
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Jun Nishihira; Mie Nishimura; Miwako Sugawara; Masafumi Kudo;
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1. Kjellmaniella crassifolia Miyabe (Gagome) Extract Modulates Intestinal and Systemic Immune Responses [J] . Huimin Yan, Shigeru Kakuta, Masao Nishihara Bioscience, Biotechnology, and Biochemistry . 2011,第11期

机译：Kjellmaniella crassifolia Miyabe（Gagome）提取物可调节肠道和全身免疫反应
2. Immune Efficacy and Safety of Fucoidan Extracted from Gagome Kombu (Kjellmaniella crassifolia) in Healthy Japanese Subjects [J] . Hiromu OHNOGI, Yuji NAITO, Yasuki HIGASHIMURA, 日本補完代替医療学会誌: JCAM . 2015,第2期

机译：Gagome Kombu（Kjellmaniella crassifolia）提取的岩藻糖苷对健康日本受试者的免疫功效和安全性。
3. Immune Efficacy and Safety of Fucoidan Extracted from Gagome Kombu (Kjellmaniella crassifolia) in Healthy Japanese Subjects [J] . Hiromu OHNOGI, Yuji NAITO, Yasuki HIGASHIMURA, 日本補完代替医療学会誌: JCAM . 2015,第2期

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7. The Safety and Immune-efficacy of Fucoidan from Gagome Kombu (Kjellmaniella crassifolia) on Women with the History of Gynecological Cancer [O] . Hoko KYO, Shintaro HASHIMOTO, Koji KOIKE, 2018

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Double-blind, parallel group, placebo-controlled study of Kjellmaniella crassifolia Miyabe (Gagome) in human: The potential of Gagome to activate the immune system

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