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首页> 外文期刊>Frontiers in Veterinary Science >Association Between Infectious Agents and Lesions in Post-Weaned Piglets and Fattening Heavy Pigs With Porcine Respiratory Disease Complex (PRDC)
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Association Between Infectious Agents and Lesions in Post-Weaned Piglets and Fattening Heavy Pigs With Porcine Respiratory Disease Complex (PRDC)

机译：断奶后仔猪和猪呼吸道疾病复合物（PRDC）育重猪的传染性药物与病变的关联（PRDC）

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Porcine Respiratory Disease Complex (PRDC) is a multifactorial syndrome that causes health problems in growing pigs and economic losses to farmers. The etiological factors involved can be bacteria, viruses, or mycoplasmas. However, environmental stressors associated with farm management can influence the status of the animal’s health. The role and impact of different microorganisms in the development of the disease can be complex, and these are not fully understood. The severity of lesions are a consequence of synergism and combination of different factors. The aim of this study was to systematically analyse samples with a standardised diagnostic protocol in case of suspected PRDC. During necropsy, the lungs and carcasses were analysed to determine the severity and extension of lesions. Gross lesions were classified according to a pre-established scheme adapted from literature. Furthermore, pulmonary, pleural, and nasal lesions were scored to determine their severity and extension. Finally, the presence of infectious agents was investigated to identify the microorganisms involved in the cases studied. During the years 2014–2016, 1658 samples of lungs and carcasses with PRDC were analysed; among them 931 and 727 samples were from weaned piglets and fattening pigs, respectively. The most frequently observed lesions were characteristic of catarrhal bronchopneumonia, broncho-interstitial pneumonia, pleuropneumonia, and pleuritis. Some pathogens identified were correlated to specific lesions, whereas other pathogens to various lesions. These underline the need for the establishment of control and treatment programmes for individual farms.
机译：猪呼吸道疾病复合物（PRDC）是一种多因素综合征，导致生长的猪和经济损失对农民的健康问题。所涉及的病因因素可以是细菌，病毒或支原体。然而，与农业管理相关的环境压力源可以影响动物健康的地位。不同微生物在疾病发展中的作用和影响可能是复杂的，而且这些不完全理解。病变的严重程度是协同作用和不同因素的结合的结果。本研究的目的是系统地分析样品，以便在疑似PRDC的情况下用标准化的诊断协议进行分析。在尸检期间，分析肺和尸体以确定病变的严重程度和延伸。根据从文献改编的预先建立的计划进行分类总病变。此外，评分肺，胸膜和鼻腔病变以确定其严重程度和延伸。最后，研究了感染性药物的存在，以鉴定所研究涉及的微生物。在2014 - 2016年期间，分析了1658年肺和尸体的肺样品;其中931和727个样品分别来自断奶仔猪和肥育猪。最常观察到的病变是Catarrhal Broncopneumonia，支气管间肺炎，胸膜炎和胸膜炎的特征。鉴定的一些病原体与特定病变相关，而其他病原体对各种病变。这些强调了为个体农场建立控制和治疗方案的必要性。

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