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Extramedullary plasmacytoma of the kidney in an HIV-positive patient: A case report

机译:艾滋病毒阳性患者肾脏尿浆浆瘤:案例报告

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Rationale: Extramedullary plasmacytoma (EMP) is a very rare malignant neoplasm arising from clonal proliferation of atypical plasma cells. Most EMPs involve mucosal lymphoid tissue, particularly in the nasopharyngeal area, respiratory tract, and head and neck region. Such neoplasms of the kidney in patients with a human immunodeficiency virus (HIV) infection are extremely rare. Patient concerns: A 55-year-old male who had been diagnosed with HIV 1 year previously presented with a 2-week history of intermittent right abdominal pain and gross hematuria. Diagnoses: Ultrasonography and computed tomography detected a mass that occupied the upper half of the right kidney . A clinical diagnosis of a renal tumor was suspected. Interventions: The patient subsequently underwent a retroperitoneal radical nephrectomy. The postoperative pathological diagnosis was solitary EMP of the kidney . Adjuvant radiation therapy was provided at doses of 50 Gy in 20 fractions. Outcomes: Currently, the patient is alive and disease free at 7 months postoperatively. To the best of our knowledge, this is the first case of a primary renal EMP in a patient with HIV. Lessons: The present case illustrates that this rare type of solitary EMP associated with acquired immune deficiency syndrome can occur in the kidney . Additionally, although rare, solitary EMP should be considered in the differential diagnosis of a renal mass in HIV-infected patients.
机译:理由:髓外血浆(EMP)是一种非常罕见的恶性肿瘤,来自非典型血浆细胞的克隆增殖。大多数EMP涉及粘膜淋巴组织,特别是在鼻咽区域,呼吸道和头部和颈部区域。患有人类免疫缺陷病毒(HIV)感染的肾脏的这种肿瘤非常罕见。患者担忧:一名55岁的男性,患有艾滋病毒1年的患者,前面患有2周的间歇性右腹痛和血尿的血腥历史。诊断:超声检查和计算机断层扫描检测到占据右肾上半部分的质量。怀疑肾脏肿瘤的临床诊断。干预措施:患者随后经历了腹膜后的根治性肾切除术。术后病理诊断是肾脏的孤立。在20个级分中以50μm的剂量提供佐剂放射疗法。结果:目前,患者在术后7个月内患有活力和疾病。据我们所知,这是艾滋病毒患者中肾脏EMP的第一种情况。课程:本例说明了与获得的免疫缺陷综合征相关的这种罕见的孤立型EMP可以发生在肾脏中。此外,虽然罕见,但在艾滋病毒感染患者肾脏肿块的差异诊断中应考虑唯一的EMP。

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