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FLAIR vascular hyperintensity-DWI mismatch most likely to benefit from recanalization and good outcome after stroke

机译:Flair血管超高度-DWI错配最有可能从中卒中后的重新化和良好的结果受益

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We assessed the value of fluid-attenuated inversion recovery vascular hyperintensity (FVH)- diffusion-weighted imaging (DWI) mismatch in predicting revascularization and functional outcome in stroke patients with large vessel occlusion (LVO) after endovascular thrombectomy (EVT). Seventy-two acute stroke patients within 6 hour of stroke onset who received EVT were enrolled. FVH-DWI mismatch, revascularization (mTICI score), functional outcome (mRS at 3 months) and other clinical data were collected. Statistical analysis was performed to predict revascularization and functional outcome after stroke . Twenty-nine patients (60.42%) had FVH-DWI mismatch in patients with complete revascularization and 8 patients (33.33%) had FVH-DWI mismatch in patients with no/partial revascularization, and there was significant difference in 2 groups ( t = 4.698; P = .045). The good functional outcome group (37/72; 51.39%) had higher FVH score (4.38 ± 1.53 vs 3.49 ± 1.52; t = 2.478; P = .016), higher FVH-DWI mismatch ratio (81.25% vs 48.15%; t = 10.862; P = .002), higher complete revascularization ratio (83.78% vs 48.57%; t = 10.036; P = .002) than the poor functional outcome group (35/72; 48.61%). Spearman's rank correlation analysis revealed that FVH-DWI mismatch was positively correlated with complete revascularization ( r = 0.255; P = .030) and good functional outcome ( r = 0.417; P = .000). Multivariable logistic regression analysis demonstrated that FVH-DWI mismatch was independently associated with complete revascularization (OR, 0.328; 95% CI, 0.117–0.915; P = .033) and good functional outcome (OR, 0.169; 95% CI, 0.061–0.468; P = .001). Assessments of FVH-DWI mismatch before thrombectomy therapy might be useful for predicting revascularization and functional outcome in stroke patients with LVO.
机译:我们评估了流体衰减的反转恢复血管超细度(FVH) - 扩散加权成像(DWI)失配的值在血管内血管切除术(EVT)后的大血管闭塞(LVO)中的血管内化和功能结果中。七十二次急性中风患者在接受EVT的6小时脑卒中后患者。 FVH-DWI不匹配,血运重建(MTICI得分),功能结果(3个月MRS)和其他临床数据被收集。进行统计分析以预测中风后血运重建和功能性结果。 29名患者(60.42%)具有完全血运重建患者的FVH-DWI失配,8名患者(33.33%)没有/部分血运重建患者FVH-DWI失配,2组差异有显着差异(T = 4.698 ; p = .045)。良好的功能结果组(37/72; 51.39%)具有更高的FVH得分(4.38±1.53 Vs 3.49±1.52; t = 2.478; p = .016),更高的FVH-DWI失配率(81.25%Vs 48.15%; t = 10.862; p = .002),更高的完全血运重建率(83.78%与48.57%; t = 10.036; p = .002)比差的功能结果组(35/72; 48.61%)。 Spearman的等级相关性分析显示,FVH-DWI错配与完全血运重建(R = 0.255; p = .030)和良好的功能结果(r = 0.417; p = .000)呈正相关。多变量逻辑回归分析证明FVH-DWI失配与完全血运重建(或0.328; 95%CI,0.117-0.915; P = .033)和良好的功能结果(或0.169; 95%CI,0.061-0.468 ; p = .001)。血液切除术治疗前FVH-DWI失配的评估对于预测LVO中风患者的血运重建和功能结果可能有用。

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