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Dietary Factors as Triggers of Low-Grade Chronic Intestinal Inflammation in Poultry

机译：饮食因素作为家禽低级慢性肠炎症的触发

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Inflammation is the reaction of the immune system to an injury; it is aimed at the recovery and repair of damaged tissue. The inflammatory response can be beneficial to the animal since it will reestablish tissue homeostasis if well regulated. However, if it is not controlled, inflammation might lead to a chronic response with a subsequent loss of tissue function. The intestine is constantly exposed to a number of environmental triggers that stimulate inflammation and lead to a reduction in performance. The diet and dietary components constitute consistent inflammatory triggers in poultry. Dietary components, such as anti-nutritional compounds, oxidized lipids, mycotoxins, and excess of soluble fiber or protein, are all capable of inducing a low-grade inflammatory response in the intestine of broilers throughout a 5-week grow-out period. We hypothesized that dietary factor-induced chronic intestinal inflammation is a key driver of the lower performance and higher incidence of intestinal problems observed in poultry production. Therefore, this review was aimed at exploring feed-induced chronic inflammation in poultry, the constituents of the diet that might act as inflammatory triggers and the possible effects of chronic intestinal inflammation on the poultry industry.
机译：炎症是免疫系统对损伤的反应;它旨在恢复受损组织的复苏和修复。炎症反应可能对动物有益，因为它将重新建立组织稳态，如果受到良好调节。但是，如果不控制，炎症可能导致慢性响应随后的组织功能。肠道不断地暴露于刺激炎症的许多环境触发器，并导致性能降低。饮食和膳食成分构成家禽中一致的炎症触发剂。膳食成分，例如抗营养化合物，氧化脂质，霉菌毒素和过量的可溶性纤维或蛋白质，全部能够在整个5周的增长期间诱导肉鸡肠道的低级炎症反应。我们假设膳食因子诱导的慢性肠炎是禽类生产中观察到的肠问题较低和肠问题的发病率的关键驱动力。因此，本综述旨在探索家禽中的饲料诱导的慢性炎症，这些饮食的成分可能充当炎症触发，以及慢性肠炎对家禽行业的可能影响。

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