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首页> 外文期刊>International Journal of Vascular Medicine >Three-Dimensional Echocardiography in Evaluating LA Volumes and Functions in Diabetic Normotensive Patients without Symptomatic Cardiovascular Disease
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Three-Dimensional Echocardiography in Evaluating LA Volumes and Functions in Diabetic Normotensive Patients without Symptomatic Cardiovascular Disease

机译：三维超声心动图在患有症状心血管疾病的糖尿病正常患者中评估La体积和功能

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Background. Cardiovascular complications are the most serious threat to diabetic patients. Associated metabolic and microvascular changes are the main cause of cardiac function affection, and the earliest cardiac change is diastolic dysfunction. Assessment of LA function changes is a key to determine early heart damage of diabetic patients. Objectives. To evaluate the effect of diabetes mellitus on left atrial volumes and functions by using real-time 3-dimensional echocardiography in normotensive patients free from cardiovascular disease. Methods. The study included 110 individuals, 50 controls and 60 patients with diabetes mellitus, 30 patients with type 1 diabetes mellitus and 30 patients with type 2 diabetes mellitus. 2-dimensional echocardiography was used to assess the LA maximum volume and LA phasic volumes, and LA maximum volume indexed to body surface area were measured by 3D echocardiography. LA functions (LA total stroke volume, LA active stroke volume, and LA active emptying fraction) were obtained from RT3D volumetric analysis. Results. The results of the analysis revealed that type 2 diabetes mellitus showed enlarged Vmax, Vmin, and LAVi with an increased LA total stroke volume and decreased active emptying fraction, while type 1 diabetics showed only decreased in active emptying fraction. The LA maximum volume indexed to body surface area (LAVi) was significantly higher in type 2 diabetic patients as compared to normal controls which was 23.55±3.37?ml/m2 versus 20.30. Conclusion. Patients with type 2 diabetes mellitus have an increased LA volume with impaired compliance and contractility, while patients with type 1 diabetes mellitus have only impaired contractility compared to nondiabetic subjects.
机译：背景。心血管并发症是对糖尿病患者最严重的威胁。相关的代谢和微血管变化是心脏功能情感的主要原因，最早的心脏变化是舒张功能障碍。评估La功能的变化是确定糖尿病患者的早期心脏损伤的关键。目标。通过使用患有心血管疾病的正常血管疾病中的实时三维超声心动图来评估糖尿病在左心房卷和功能的影响。方法。该研究包括110名患有110名糖尿病患者，30名患有1型糖尿病患者和30名糖尿病患者。二维超声心动图用于评估La最大体积和千相体积，并通过3D超声心动图测量对体表面积的La最大体积。从RT3D容量分析获得La功能（La总冲程量，La主动冲程体积和La主动排空级分）。结果。分析结果表明，2型糖尿病患者显示vmax，vmin和Lavi的增大，La总冲程量增加，并且活性排空分数降低，而1型糖尿病患者显现出在活性排空级分中仅降低。与正常对照相比，2型糖尿病患者的体表面积（Lavi）指数的La最大体积显着高于23.55±3.37Ω×M1 / M2与20.30。结论。患有2型糖尿病的患者具有增加的LA体积，依从性和收缩性损害，而1型糖尿病患者仅与非糖尿病受试者相比仅受损的收缩性。

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