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首页> 外文期刊>Molecular and Cellular Biomedical Sciences: MCBS >Correlation between Protein Intake, Fat Free Mass, and Total Lymphocyte Count with Quality of Life in Pulmonary Tuberculosis Patients Undergoing Intensive Phase Treatment in Pekanbaru, Riau Province
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Correlation between Protein Intake, Fat Free Mass, and Total Lymphocyte Count with Quality of Life in Pulmonary Tuberculosis Patients Undergoing Intensive Phase Treatment in Pekanbaru, Riau Province

机译：玉米菌肺结核患者患者蛋白摄入，脂肪含量和总淋巴细胞数与肺结核患者患者的肺结核患者的相关性相关性

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Background: Malnutrition and tuberculosis (TB) have a bidirectional relationship, which interacts between each other. In chronic infection, there is an imbalance between protein degradation and protein synthesis which marked with the loss of fat-free mass (FFM). Malnutrition can cause the atrophy of the thymus gland resulted in the reduction of lymphocyte production. Malnutrition in TB patients will reduce the quality of life. On the other hand, a good quality of life will increase the treatment success rate and decrease the risk of morbidity and mortality. Materials and Methods: A cross-sectional study was conducted in 12 primary health centers (PHC) chosen randomly from 23 PHC in Pekanbaru, Riau Province. The random selection was performed by using simple random sampling (random number generator). Data were collected from May until July 2019. Samples were selected using a consecutive sampling method and 72 subjects fulfilled all research criteria. The interview was used to collect basic characteristic data, dietary intake data, and quality of life score. Anthropometric measurement (body weight, body height, and FFM) and laboratory examination (total lymphocyte count) were done. Results: Research showed median age subjects was 33 years old (18-59 years old). Most of the subjects were male (56.9%), had a middle level of education, low income, were active smokers with underweight nutritional status. More than 50% of subjects had low protein intake, low fat-free mass, normal lymphocyte count and had a good quality of life. Conclusion: There was a statistically significant correlation between fat-free mass with PCS (r=0.239, p =0.044), but not for protein intake and total lymphocyte count.
机译：背景：营养不良和结核病（TB）具有双向关系，彼此之间相互作用。在慢性感染中，蛋白质降解和蛋白质合成之间存在不平衡，其标记为无脂肪质量（FFM）的损失。营养不良会导致胸腺腺体的萎缩导致淋巴细胞产生的减少。 TB患者的营养不良将降低生活质量。另一方面，良好的生活质量将增加治疗成功率并降低发病率和死亡率的风险。材料和方法：在瑞秋省Pekanbaru 23 PhC中随机选择的12个主要保健中心（PHC）进行横截面研究。通过使用简单的随机采样（随机数发生器）来执行随机选择。从5月到2019年7月收集数据。使用连续采样方法选择样品，72个受试者满足所有研究标准。面试用于收集基本特征数据，饮食进口数据和生活质量分数。完成人体测量（体重，体高，FFM）和实验室检查（总淋巴细胞计数）。结果：研究表明中位年龄受试者33岁（18-59岁）。大多数受试者是男性（56.9％），中期教育，低收入，是活跃的吸烟者，营养状况不足。超过50％的受试者具有低蛋白质摄入量，无脂肪含量低，正常淋巴细胞计数，具有良好的生活质量。结论：PCS的无脂肪质量之间存在统计学上显着的相关性（r = 0.239，p = 0.044），但不适用于蛋白质摄入和总淋巴细胞计数。

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