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首页> 外文期刊>Neuroscience Journal >Impact of Tooth Loss and Other Risk Factors on Cognitive Impairment in Saudi Female Population
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Impact of Tooth Loss and Other Risk Factors on Cognitive Impairment in Saudi Female Population

机译：牙齿损失与其他危险因素对沙特女性人口认知障碍的影响

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Introduction. It is known that cognitive impairment is linked to aging and neurobiological, psychological, and social factors. Recently, however, mastication and the number of teeth has also attracted attention, with a previous case control study reporting a correlation between the loss of teeth and Alzheimer’s disease. Objective. To investigate possible relationships between cognitive function and various demographic variables, stress, medical history, and number of natural teeth in a specified female population. Materials & Methods. A sample of the Saudi female population, 40–65 years of age, who visited the King Khalid University College of Dentistry (Abha, Saudi Arabia), was studied. Education, occupation, perceived stress, and medical history, along with the number of remaining teeth, were assessed. The Mini-Mental State Examination (MMSE) was used to assess cognitive performance and the results were statistically analyzed. Results. Subjects were divided into those with mild, moderate, and severe impairment based on MMSE score; the association between age, education, occupation, medical history, and cognitive function demonstrated statistically significant results. Fifty percent of subjects with 0–16 teeth exhibited severe cognitive impairment. Of the cognitive abilities, attention, recall, and language skills were linked to the number of remaining teeth. When subjects were categorized into only high and low cognitive impairment based on MMSE score, regression analysis did not reveal a significant correlation between any of the studied variables and cognitive impairment. Conclusion. Results of the present study add to the recent data and head towards the theory of likely connection between the number of teeth and hippocampus-dependent cognitive functioning. Results of regression analysis revealed an absence of conclusive relation in the latter part of study. Longitudinal analyses including comprehensive clinical dental data with brain-imaging will shed further light on probable causal relationship(s).
机译：介绍。众所周知，认知障碍与老龄化和神经生物学，心理和社会因素有关。然而，最近，咀嚼和牙齿的数量也引起了注意力，并进行了先前的病例对照研究，报告了牙齿丧失与阿尔茨海默病之间的相关性。客观的。研究认知功能与各种人口变量，压力，病史和特定女性人群中的天然牙齿数量的可能关系。材料与方法。研究了40-65岁的沙特女性人口样本，研究了哈立德大学牙科王室（Abha，沙特阿拉伯）。评估教育，占领，感知的压力和病史以及剩下的牙齿的数量。迷你精神状态检查（MMSE）用于评估认知性能，结果统计学分析。结果。基于MMSE评分，受试者分为患有轻度，中等和严重损害的受试者;年龄，教育，职业，病史和认知功能之间的关联表现出统计上显着的结果。患有0-16颗牙齿的百分之五十个患者表现出严重的认知障碍。认知能力，关注，回忆和语言技能与剩余牙齿的数量有关。当受试者仅基于MMSE评分仅分为高低认知障碍时，回归分析没有揭示任何研究变量与认知障碍之间的显着相关性。结论。本研究的结果增加了最近的数据和头部，朝向牙齿数量和海马依赖认知功能之间的可能连接的理论。回归分析结果表明，在后期的研究中没有结论性关系。纵向分析包括脑成像的综合临床牙科数据将在可能的因果关系中进一步发光。

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