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首页> 外文期刊>Nigerian Journal of Physiological Sciences >Resting serum concentration of high-sensitivity C-reactive protein (hs-CRP) in sportsmen and untrained male adults
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Resting serum concentration of high-sensitivity C-reactive protein (hs-CRP) in sportsmen and untrained male adults

机译：在运动员和未经训练的男性成年中休息高敏性C反应蛋白（HS-CRP）的血清浓度

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There is an inverse relationship between regular physical activity and concentration of serum inflammatory markers, with variations in resting CRP in trained and? untrained subjects. The effect of acute and prolonged exercises has been studied on inflammatory markers with dearth of information and controversies on the resting serum values of high sensitivity CRP (hs-CRP). Therefore, this study sought to? identify and compare variations that occur in serum levels of high sensitivity CRP in groups of sportsmen (6) and physically active untrained subjects. Eighty-one healthy male participants made up of 21 untrained (control), 10 footballers, 10 athletes, 10 karates, 10 volleyballers, 10 basketballers, and 10 baseballers? voluntarily participated in the study. Participants rested while in sitting position for about 30 minutes during which blood pressures and heart rates were taken. 5 mls of venous blood was withdrawn from the antecubital vein of the participants? (aseptically) between 7:00 and 10:00 am into lithium heparin bottles following an overnight fast. The supernatant was decanted and centrifuged at 3000 rpm, serum was collected and stored at -20oC prior to biochemical assay which was done with the use of enzyme linked immunosorbent assay (ELISA) kits for hs-CRP. Differences in the means within the sporting groups were analysed using one-way ANOVA while the difference between the trained sportsmen and untrained young adults was analysed using the independent T-test. Statistical significance was set at p 0.05. The Mean ±SEM age, weight, height, and BMI of the participants were 22.0±0.8 years, 64.1±2.2 kg, 1.74±0.3 m, and 20.6±0.2 kg/m2 respectively. The resting concentration of hs-CRP (μg/ml) was 1.0±0.2 in the untrained, 2.6±0.7 in footballers, 3.6±2.1 in track athletes, 2.4±0.5 in basketballers, 2.2±0.5 in volleyballers, 2.4±1.3 in baseballers, and 1.7±0.5 in karate respectively. There was no significant difference in the resting hs-CRP amongst the sporting groups, and in the sportsmen and untrained group. Resting serum levels of hs-CRP falls within normal range, and varies insignificantly in groups of sports, and in sportsmen and untrained young male adults. This may suggest that the types of sporting activities or participation in sports has no impact on the resting serum hs-CRP.
机译：常规身体活性和血清炎症标志物的浓度之间存在反比关系，具有培训的休息CRP的变化和？未经训练的科目。已经研究了急性和长期锻炼的效果，对炎症标志物，具有缺乏信息和高灵敏度CRP（HS-CRP）静息血清值的争论。因此，这项研究寻求？鉴定并比较运动员（6）组和身体活跃未经训练的受试者的高灵敏度CRP中发生的血清水平的变化。八十一位健康的男性参与者由21名未经训练（控制），10名足球运动员，10名运动员，10名空手道，10名排球运动员，10名篮球运动员和10名棒球运动员？自愿参加了这项研究。参与者在坐姿休息约30分钟，在此期间血压和心率。从参与者的抗腊肠静脉中取出了5毫升静脉血？ （无视野）在7:00至10:00之间进入肝素瓶后，在一夜之间快速。将上清液以3000rpm滗析并离心，在生物化学测定之前收集3000rpm，在-20℃下储存，这是使用酶连接的免疫吸附测定（ELISA）试剂盒进行HS-CRP进行的。使用单向ANOVA分析体育群体内的手段的差异，而使用独立的T检验分析培训的运动员和未经训练的年轻成人之间的差异。统计显着性设定为P <0.05。参与者的平均值±SEM年龄，体重，高度和BMI分别为22.0±0.8岁，分别为64.1±2.2千克，1.74±0.3米和20.6±0.2千克/平均值。在未受伤的HS-CRP（μg/ ml）的静浓度为1.0±0.2，在足球运动员中为2.6±0.7，轨道运动员3.6±2.1，篮球运动员2.4±0.5，排球运动员2.2±0.5，棒球运动员2.4±1.3分别在空手道中的1.7±0.5。在体育群体中休息的HS-CRP以及运动员和未经培训的群体中休息的HS-CRP没有显着差异。将血清水平的HS-CRP水平落在正常范围内，体育群体和运动员和未经训练的年轻男性成年人之间不关要。这可能表明体育活动或参与体育的类型对静止的血清HS-CRP没有影响。

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