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首页> 外文期刊>Open Journal of Urology >Comparative Study of Cell Findings by Conventional Smear and Liquid-Based Cytology for Oral Exfoliative Cytology
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Comparative Study of Cell Findings by Conventional Smear and Liquid-Based Cytology for Oral Exfoliative Cytology

机译：常规涂片和液相基细胞学对口腔剥离细胞学细胞学细胞的比较研究

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Background: ?Liquid-based cytology?(LBC) is a method of manufacturing cyto-diagnostic specimens. Improved accuracy is expected from standardizing specimen production and use of this method is rapidly spreading in oral cytology. On the other hand, LBC reportedly requires training to show peculiar cell findings compared to those of conventional smear cytology (CVC). Few studies have compared detailed cell findings for oral CVC and LBC. ? Objec tives: ?The aim of this study was to compare cytological findings between CVC and LBC using cytomorphological image analysis. ? Materials and Methods: ?Cytological specimens were collected from 20 patients (negative for squamous neoplasia in 10, dysplasia in 5, squamous cell carcinoma in 5) and 5 controls of the tongue between January 2017 and December 2018. Two different preparation techniques were investigated cytomorphologically for CVC and LBC (BD Cytorich ~( TM ) ). ? Results: ?LBC showed significantly higher cell numbers tha n CVC for all lesions. LBC-to-CVC ratio ranged from 9.52 (hyp erkeratosis) to 1.87 (deep cells in oral squamous cell carcinoma (OSCC)). Nuclear area of normal, hyperkeratosis, and inflammation were significantly higher in LBC tha n those of CVC. Hyperchromasia was significantly more frequent with CVC than with LBC for hyperkeratosis, inflammation, dysplasia and OSCC. There was no significant difference in circularity between CVC and LBC among all lesions. Conclusion: ?Only one cytomorphological disadvantage was se en with LBC, in the form of decreased hyperchromasia. Further clarification of the advantages and disadvantages of LBC is needed, including management of precision and screening practices.
机译：背景：α液体细胞学？（LBC）是制造细胞诊断标本的方法。预计标准化标本生产和使用这种方法的使用是提高的准确度在口腔细胞学中迅速蔓延。另一方面，据报道，与常规涂片细胞学（CVC）相比，LBC需要培训以显示奇形的细胞发现。很少有研究对口服CVC和LBC进行了比较了详细的细胞发现。 ？ objec tives：？本研究的目的是使用细胞骨髓图像分析比较CVC和LBC之间的细胞学发现。 ？ 材料和方法：？从20名患者收集细胞学标本（10例，5，5，5，鳞状细胞癌5，5）和2018年1月之间的舌头控制，两种不同的准备技巧对CVC和LBC进行细胞形态（BD Cytorich〜（Tm））进行了调查。 ？ 结果：α1BC显示出所有病变的显着更高的细胞数Tha N CVC。 LBC-to-CVC比率范围为9.52（次次肉肌瘤）至1.87（口腔鳞状细胞癌（OSCC）中的深细胞）。 CVC的LBC Tha N的正常性，高畸形病和炎症的核领域显着高。 CVC的高胆大差异比LBC用于高表情，炎症，发育不良和OSCC。所有病变中CVC和LBC之间的圆形无统计学差异。 结论：α只有一种细胞素孤独的缺点是LBC，以减少的高胆大症的形式。进一步澄清LBC的优缺点，包括精确和筛选实践的管理。

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