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Hypercapnia at Hospital Admission as a Predictor of Mortality

机译:医院入院的Hypercapnia作为死亡率的预测

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Introduction: Hypercapnia is an indicator of ventilatory exhaustion. There is some disagreement regarding whether hypercapnia is also a predictor of mortality. In this prospective study, we aimed to investigate whether hypercapnia can predict in-hospital and 1-year mortality rates in patients with dyspnea or pulmonary diseases. Patients and Methods: All patients with dyspnea or pulmonary diseases underwent routine blood gas analysis at hospital admission. During the 12-month enrollment period, 2710 patients were enrolled, and 588 patients with hypercapnia at admission were identified. Of the 1626 normocapnic patients, 62 were randomly selected as controls. In-hospital and 1-year mortality rates were determined. Results: There were significant increases in mortality rate between acute hypercapnic patients and both chronic hypercapnic patients and normocapnic controls. Their in-hospital mortality rates were 17%, 6.7% and 3.2%, respectively. Their 1-year mortality rates were 32%, 20.2% and 14.5%, respectively. The 1-year mortality rates of hypercapnic patients with different underlying diseases were 24.6% (chronic obstructive pulmonary disease), 28.4% (congestive heart disease), 1.6% (obstructive sleep apnea syndrome/obesity hypoventilation syndrome), 50.9% (pneumonia), 0% (suppressed central respiratory drive, primarily due to opiate abuse) and 22.8% (other conditions). Discussion: The 1-year mortality rate of patients with acute hypercapnia at hospital admission was 32%, with significant differences compared to chronic hypercapnic patients (20.2%) and normocapnic patients (14.5%). There was a wide range of 1-year mortality rates between the hypercapnic patients with different underlying diseases.
机译:简介:Hypercapnia是通风耗尽的指标。关于Hypercapnia是否也是死亡率的预测因素存在一些分歧。在这项前瞻性研究中,我们旨在调查Hypercapnia是否可以预测呼吸困难或肺病患者的医院和1年的死亡率。患者及方法:所有患有呼吸困难或肺病的患者在医院入院时经历了常规血气分析。在12个月的入学期间,注册了2710名患者,并确定了588例患有588名患有的患者。在1626名NormoCapnic患者中,62例被随机选择作为对照。在医院和1年的死亡率率确定。结果:急性高钙患者与慢性高型患者和炔诺人控制之间的死亡率显着增加。他们的住院死亡率分别为17%,6.7%和3.2%。他们的1年死亡率分别为32%,20.2%和14.5%。患有不同潜水疾病的1年性患者的死亡率为24.6%(慢性阻塞性肺病),28.4%(充血性心脏病),1.6%(阻塞性睡眠呼吸暂停综合征/肥胖呼吸悬浮综合征),50.9%(肺炎), 0%(抑制中央呼吸驱动,主要是由于鸦片滥用)和22.8%(其他条件)。讨论:医院入院急性高腺癌患者的1年死亡率为32%,与慢性高碳化患者(20.2%)和NormoCapnic患者(14.5%)相比,差异显着。患有不同潜在疾病患者的杂质患者之间存在广泛的1年死亡率。

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