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首页> 外文期刊>Sao Paulo Medical Journal >Fine particulate matter and ischemic heart diseases inrelation to sex. An ecological time series study
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Fine particulate matter and ischemic heart diseases inrelation to sex. An ecological time series study

机译：与性有关的细颗粒物质和缺血性心脏病。生态时间序列研究

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BACKGROUND: Exposure to some air pollutants is associated with cardiovascular diseases. The objective of this study was to quantify the effect of exposure to fine particulate matter in hospitalizations due to ischemic heart disease and the costs to the healthcare system. DESIGN AND SETTING: Time-series ecological study conducted in Taubaté, Brazil. METHODS: Data on hospitalizations due to ischemic heart diseases (ICD I-20 to I-24) in the municipality of Taubaté (SP), Brazil, among adults of both sexes aged 40 years and over, from August 2011 to July 2012, were obtained from DATASUS. Fine particulate matter (PM2.5) concentrations were estimated from a mathematical model. Poisson regression was used in statistical analyses to estimate the relative risks of exposure to PM2.5 for both sexes and after stratification according to sex. The excess of hospitalizations and consequent excess expenditure for the healthcare system were calculated. RESULTS: There were 1040 admissions, among which 382 had ischemic heart diseases (257 males). Themean PM2.5 concentration was 13.2 μg/m3 (SD = 5.6). Significant effects from exposure were noted 4and 5 days after exposure (lag 4 and lag 5) for both sexes and for male sex; for female sex, the effect was 2 days after exposure (lag 2). There were 59 excess hospitalizations for an increase in PM2.5 concentration of 5 μg/m3 and excess expenditure of US$ 150,000 for the National Health System. CONCLUSIONS: An excess of hospital admissions due to ischemic heart disease, with excess expenditure, was identified consequent to PM2.5 exposure.
机译：背景：暴露于一些空气污染物与心血管疾病有关。本研究的目的是由于缺血性心脏病和医疗保健系统的成本，量化暴露于住院中细颗粒物质的影响。设计与环境：巴西Taubaté进行的时间系列生态学研究。方法：在2011年8月至2012年8月至7月，巴西，巴西在巴西（SP）的喀布特岛（SP）市内的缺血性心脏病（ICD I-20至I-24）所缺血性心脏病（ICD I-20至I-24）的住院数据。从数据群中获取。从数学模型估计细颗粒物质（PM2.5）浓度。泊松回归用于统计分析，以估算对性别的暴露于PM2.5的相对风险，以及根据性别的分层。计算出院的过剩和随之而来的医疗保健系统的超额支出。结果：有1040个录取，其中382人患有缺血性心脏病（257名男性）。主题PM2.5浓度为13.2μg/ m 3（SD = 5.6）。暴露于暴露（滞后4和滞后5）后4和男性性别，注意到暴露的显着效果;对于女性，曝光后的效果是2天（滞后2）。有59种过剩的住院治疗，增加PM2.5浓度为5μg/ m3，全国卫生系统的支出超过150,000美元。结论：由于缺血性心脏病，支出超过支出，因此对PM2.5接触产生过多的医院入院。

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