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首页> 外文期刊>Sao Paulo Medical Journal >SARS-CoV-2 and arbovirus infection: a rapid systematic review
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SARS-CoV-2 and arbovirus infection: a rapid systematic review

机译：SARS-COV-2和Arbovirus感染：快速系统审查

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BACKGROUND: The numbers of cases of arboviral diseases have increased in tropical and subtropical regions while the coronavirus disease (COVID-19) pandemic overwhelms healthcare systems worldwide. The clinical manifestations of arboviral diseases, especially dengue fever, can be very similar to COVID-19, and misdiagnoses are still a reality. In the meantime, outcomes for patients and healthcare systems in situations of possible syndemic have not yet been clarified. OBJECTIVE: We set out to conduct a systematic review to understand and summarize the evidence relating to clinical manifestations, disease severity and prognoses among patients coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and arboviruses. METHODS: We conducted a rapid systematic review with meta-analysis, on prospective and retrospective cohorts, case-control studies and case series of patients with confirmed diagnoses of SARS-CoV-2 and arboviral infection. We followed the Cochrane Handbook recommendations. We searched EMBASE, MEDLINE, Cochrane Library, LILACS, Scopus and Web of Science to identify published, ongoing and unpublished studies. We planned to extract data and assess the risk of bias and the certainty of evidence of the studies included, using the Quality in Prognosis Studies tool and the Grading of Recommendations Assessment. RESULTS: We were able to retrieve 2,407 citations using the search strategy, but none of the studies fulfilled the inclusion criteria. CONCLUSION: The clinical presentations, disease severity and prognoses of patients coinfected with SARS-CoV-2 and arboviruses remain unclear. Further prospective studies are necessary in order to provide useful information for clinical decision-making processes. Protocol registration number in the PROSPERO database: CRD42020183460.
机译：背景：在热带和亚热带地区的群体疾病患者的数量增加，而冠状病毒疾病（Covid-19）大流行势在量全球医疗保健系统。枝胺病毒疾病，特别是登革热，可以与Covid-19非常相似的临床表现，并且误诊仍然是现实。与此同时，尚未澄清在可能的对象的情况下患者和医疗保健系统的结果。目的：我们旨在进行系统审查，以了解和总结与临床表现，疾病严重程度和携带的严重急性呼吸综合征冠状病毒2（SARS-COV-2）和腹膜病毒有关的临床表现，疾病严重程度和预期的证据。方法：对荟萃分析，对患者进行了快速系统的审查，对核心分析，病例对照研究和案例系列患者进行了确诊的SARS-COV-2和仲裁感染。我们跟随Cochrane手册建议。我们搜索了Embase，Medline，Cochrane图书馆，丁香，Scopus和科学网站，以识别出版，正在进行和未发表的研究。我们计划提取数据并评估偏见的风险以及使用预后研究工具的质量和建议评估的评分所包括的研究证书的肯定。结果：我们能够使用搜索策略检索2,407引文，但没有符合纳入标准的研究。结论：用SARS-COV-2和腹膜病毒携带患者的临床介绍，疾病严重程度和预测仍然尚不清楚。进一步的预期研究是必要的，以便为临床决策过程提供有用的信息。 Prospero数据库中的协议注册号：CRD42020183460。

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