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首页> 外文期刊>Saudi Journal of Anaesthesia >Effect of addition of magnesium to local anesthetics for peribulbar block: A prospective randomized double-blind study
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Effect of addition of magnesium to local anesthetics for peribulbar block: A prospective randomized double-blind study

机译：将镁添加到Peribulbar块局部麻醉剂的影响：一项前瞻性随机双盲研究

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Background: Magnesium sulphate has been used along with local anesthetics in different regional blocks and found to be effective in decreasing the time of onset of the block and increasing the duration of the block. Objective: To evaluate the effect of addition of magnesium sulfate to standard local anesthetics mixture on the time for onset of the globe and lid akinesia for peribulbar block in ophthalmic surgeries. Materials and Methods: Sixty patients with American Society of Anesthesiologists status I to III undergoing ophthalmic surgery under peribulbar block were included in this study. Patients were randomized into two groups. Both the groups received 4.5 ml of 2% lidocaine, 4.5 ml of 0.5% bupivacaine with150 IU hyaluronidase. Group NS received normal saline 1 ml in the peribulbar block and Group MS, magnesium sulfate 50 mg in 1 ml normal saline. The onset of akinesia, satisfactory block and complications were observed by an independent observer. Results: Demographic data was statistically similar. In the Group NS at 3, 5, 10 and 15 min after the block, complete akinesia was seen in 0, 2, 11 and 28 patients respectively. In the Group MS, at 3, 5, 10 and 15 min after the block, complete akinesia was seen in 13, 23, 27 and 28 patients respectively. Patients received magnesium sulfate showed the statistically significant rapid onset of lid and globe akinesia than the control group till 10 min ( P < 0.000). None of the patients needed a supplementary block and had complications during the surgery. Conclusion: Addition of 50 mg of magnesium sulfate to the lidocaine-bupivacaine mixture for peribulbar block decreases the onset of akinesia without any obvious side effect.
机译：背景：硫酸镁在不同的区域嵌段中与局部麻醉剂一起使用，发现在降低块的发作时间并增加块的持续时间有效。目的：评价硫酸镁对标准局部麻醉剂混合物的效果，在眼科手术中蠕动植物植物植物植物杆菌肿瘤的时间。材料与方法：六十六里的美国麻醉学家患者地位I至III在这项研究中纳入了Peribulbar块下的眼科手术。患者被随机分为两组。两组均接受4.5ml 2％利多卡因，4.5mL 0.5％Bupivacaine，具有150 IU透明质酸酶。 NS在Peribulbar嵌段中接受了正常的盐水1mL，将MS，硫酸镁在1mL甘露出盐中的硫酸镁。通过独立观察者观察到αskinesia，令人满意的障碍和并发症的发作。结果：人口统计数据在统计上类似。在嵌段后3,5,10和15分钟的NS中，分别在0,2,11和28名患者中观察到完整的Akinesia。在嵌段后3,5,10和15分钟的组中，分别在13,23,27和28名患者中观察到3,5,10和15分钟。患者接受硫酸镁显示盖子和全球菌落的统计显着快速发作，比对照组直至10分钟（P <0.000）。没有患者在手术期间需要补充块并具有并发症。结论：向Peribulbar块的Lid Caine-Bupivacaine混合物中加入50mg硫酸镁，降低了αINIA的发作而没有任何明显的副作用。

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