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首页> 外文期刊>Sri Lanka Journal of Forensic Medicine, Science & Law >A short review on the use of short tandem repeat based DNA profiling in sexual assault
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A short review on the use of short tandem repeat based DNA profiling in sexual assault

机译:关于在性侵犯中使用短串联重复的DNA分析的简短综述

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摘要

Forensic DNA evidence can convict perpetrators who would otherwise have escaped, hence the reason for its growth in case evidence over the years. Short Tandem Repeat (STR) profiling, continues to be the mainstay for forensic DNA testing due to its robustness and high power of discrimination. The ‘core STRs’ in forensics, are highly polymorphic, and unique to an individual, therefore proven as important investigative leads in cases of identification of perpetrators in sexual assault, thereby ensuring justice. The common STRs used to date are autosomal STRs, Y-STRs, mini STRs and recently, Deletion Insertion Polymorphism-STRs. This article reviews current literature and discusses the advantages and limitations of each STR marker and their targets in different challenging samples. It aims to provide intuition on minimising ambiguous profiles for case evidence in sexual assault and thereby, reduce the chances of wrongful conviction by DNA evidence.
机译:法医DNA证据可以判定违反犯罪者的肇事者,因此在多年来证据证据的增长原因。短串联重复(str)分析,仍然是由于其鲁棒性和辨别力的高功率导致法医DNA测试的主干。在法医学中的“核心strs”是高度多态性的,而且个人是独一无二的,因此被证明是在识别性侵犯中识别肇事者的重要调查导线,从而确保正义。迄今为止迄今为止的常见条件是常染色剂STRS,Y-STRS,MINI STRS,最近,删除插入多态性-trs。本文审查了当前的文献,并探讨了每个STR标记的优缺点及其目标在不同具有挑战性的样本中。它旨在为最小化性侵犯案例证据最大限度地减少模棱两可的曲线,从而提供了DNA证据的错误定罪的机会。

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