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The scope of tobacco cessation randomized controlled trials in low- to middle-income countries: protocol for a scoping review

机译：烟草停止随机对照试验的范围在低至中等收入国家：范围审查的议定书

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摘要

Tobacco consumption is the leading cause of preventable death globally. The global mortality burden of tobacco use lies predominantly in low- to middle-income countries (LMICs). There is much evidence on the effectiveness of tobacco cessation RCTs in high-income nations. However, the evidence base in LMICs is far more limited. To effectively design randomized controlled trials (RCTs) that mitigate tobacco-related harms in LMICs, further understanding of RCTs in this environment will be helpful. We will provide quality evidence regarding the scope of tobacco cessation RCTs in LMICs. A scoping review of tobacco cessation RCTs will be conducted. MEDLINE, Embase, PsycINFO, Global Health, Web of Science and Sociological Abstracts will be searched to capture current literature. We will review RCTs that have already been done on tobacco cessation in the LMICs. The key outcome will be tobacco cessation in adults. Examples of the key outcome include smoking abstinence and reduction of tobacco use. Study selection will conform to Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) guidelines and study quality assessed with a modified version of the Cochrane Collaboration’s instrument. As researchers attempt to minimize the harms from tobacco in LMICs, they need to be aware of scientific evidence to develop RCTs to achieve their aim. The review will complement the evidence base on tobacco cessation in LMICs.
机译：烟草消费是全球可预防死亡的主要原因。烟草使用的全球死亡负担主要位于低收入中等收入国家（LMIC）。有很多关于烟草停止RCT在高收入国家的有效性的证据。但是，LMIC中的证据基础远远有限。为了有效地设计在LMIC中减轻烟草相关危害的随机对照试验（RCT），在这种环境中进一步了解RCT将有所帮助。我们将为LMIC中的烟草停止RCT的范围提供质量证据。将进行对烟草停止RCTS的范围审查。将搜索Medline，Embase，Psycinfo，全球健康，科学和社会学摘要，以捕捉当前的文献。我们将审核已经在LMICS中删除烟草的RCT。关键结果将是成年人的烟草停止。关键结果的实例包括吸烟戒烟和减少烟草使用。学习选择将符合Sysocation评论和Meta-Analyses延伸的首选报告项目，用于划分的评论（Prisma-SCR）指南和学习质量评估的Cochrane协作的仪器。随着研究人员试图最大限度地减少烟草中的烟草中的危害，他们需要了解科学证据来发展RCT以实现其目标。审查将补充LMICS中烟草停止的证据基础。

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