ROLE OF MOMORDICA CHARANTIA L. AS HERBAL MEDICINE TO CURE HYPERGLYCEMIA IN VITRO ON INDUCED DIABETIC MODEL ANIMALS WAHEEDA MUSHTAQ1*, M TARIQ2, M. ISHTIAQ1*, R. ASGHAR2, TANVEER HUSSAIN1 AND TANVEER BASHIR

M. ASIF; M. FARRAKH NAWAZ; M.T. SIDDIQUI; ABDUL HANNAN; SADAF GUL; SALMAN AHMED; IRFAN AHMAD; M. ATIQ

摘要

Dieback disease is a potential threat to Dalbergia sissoo (Shisham) which is a multipurpose tree of the Indiansubcontinent. Different factors have been found associated with inciting shisham dieback. Fungal pathogens have beenrecognized as the major causal organism but changing climate is a main threat to forest dieback. Sexually (seedlings) andasexually (cuttings) propagated shisham were inoculated with the different fungi (Fusarium solani, Botryodiplodiatheobromae, Curvularia lunata and Ganoderma lucidum). As environmental factors play critical role in the development ofthe disease, so the present study was designed to observe the impact of rainfall, temperature, relative humidity and windvelocity on the disease and for the management of disease predictive model was developed. A significant negativecorrelation was observed between disease and relative humidity both for seedlings (r = - 0.97) and cuttings (r = -0.487),respectively while maximum temperature expressed significant positive correlation with seedlings and cuttings withcoefficient of correlation r = 0.734 and r = 0.629, respectively. Path analysis expressed that with one unit increase in rainfallthe disease would rise by 7.58 and 15.04 and for maximum temperature it was 2.47 and 5.27 units in seedlings and cuttings,respectively. Multiple regression analysis showed that coefficient of determination (R2) value was 0.62 and 0.48 for cuttingsand seedlings, respectively. Normed fit index (NFI) and comparative fit index (CFI) values indicate that model is quite agood fit. Similarly comparison of observed and predicted data also validated the model for forecasting the disease.

机译：DieBack疾病是对达伯利亚罗（Shisham）的潜在威胁，这是印度化的多用途树。已发现不同因素与煽动Shisham Dieback相关联。真菌病原体已被认为是主要的因果生物，但不断变化的气候是对森林死刑的主要威胁。性（幼苗）Andasex上（Cuttings）繁殖的Shisham被不同的真菌（镰刀菌，BotryodiaSheobromae，Curvularia Lunata和Ganoderma lucidum）接种。由于环境因素在疾病的发展中发挥着关键作用，因此目前的研究旨在观察降雨，温度，相对湿度和风素对疾病的影响，并为疾病预测模型进行管理。对于幼苗（R = - 0.97）和切割（R = -0.487）的疾病和相对湿度之间观察到显着的否定症状，而最高温度表达与幼苗和扦插的显着正相关性，并且相关性r = 0.734和r = 0.629 ，分别。路径分析表明，在降雨量的增加中，疾病的增加将增加7.58和15.04，其最高温度分别为2.47和5.27个幼苗和切割装置。多元回归分析表明，用于切屑和幼苗的测定系数（R2）值为0.62和0.48。规范的拟合指数（NFI）和比较拟合指数（CFI）值表明模型是非常适合的。类似地，观察和预测数据的比较也验证了预测疾病的模型。

ROLE OF MOMORDICA CHARANTIA L. AS HERBAL MEDICINE TO CURE HYPERGLYCEMIA IN VITRO ON INDUCED DIABETIC MODEL ANIMALS WAHEEDA MUSHTAQ1, M TARIQ2, M. ISHTIAQ1, R. ASGHAR2, TANVEER HUSSAIN1 AND TANVEER BASHIR

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