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首页> 外文期刊>Patient Preference and Adherence >Clopidogrel-taking behavior by drug-eluting stent patients: Discontinuers versus continuers
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Clopidogrel-taking behavior by drug-eluting stent patients: Discontinuers versus continuers

机译：氯吡格雷采取的药物洗脱支架患者的行为：中断与连续者

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Background: Each day, patients make choices whether or not to take their prescribed medications. Previous research has shown that 1 in 7 myocardial infarction (MI) patients discontinued thienopyridines within 1 month of receiving a drug-eluting stent (DES) with serious consequences. This qualitative research study explored in depth the clopidogrel-taking behavior among DES-treated patients who quit taking clopidogrel 1 month after treatment and those who continued therapy.Methods: Sequential patients from a prospective MI registry who reported discontinuing clopidogrel within 30 days of DES treatment (N = 11) were matched with continuers (N = 11). Both groups underwent detailed qualitative phone interviews. Coding and thematic representation using directed qualitative content analysis by 3 PhD researchers was done.Results: Patients were 41–77 years old and the majority was Caucasian and male. Multiple barriers were described by discontinuers that were not reported by continuers. The most frequently cited barrier was misunderstanding the intended duration of treatment. Discontinuers also described system weaknesses that contributed to early discontinuance such as gaps in the transition to primary care.Conclusions: While premature discontinuation of a prescribed therapy is viewed by clinicians as a willful disregard for medical advice, early stopping of clopidogrel is influenced greatly by processes of care and system issues.
机译：背景：每天，患者做出选择是否服用规定的药物。以前的研究表明，在7个心肌梗死（MI）患者中，在接受药物洗脱支架（DES）的1个月内停止噻吩吡啶，具有严重后果。这种定性研究探讨了在治疗后1个月的氯吡格雷患者和持续治疗的那些撤回氯吡格雷的氯吡格雷的行为中探讨了氯吡格雷的行为。方法：从预期MI登记处的顺序患者报告在DES治疗后30天内停止氯吡格雷。 （n = 11）与连续者（n = 11）匹配。两组都接受了详细的定性电话访谈。使用3个博士学位研究人员使用指向定性内容分析的编码和主题表示。结果：患者41-77岁，大多数是高加索人和男性。通过不断报告的中断者描述了多个障碍。最常见的屏障误解了预期的治疗持续时间。中断人员还描述了有助于早期停止的系统缺点，例如转型到初级保险的差距。结论：临床医生认为，临床医生视为医疗建议的故意无视临床的过早停止，氯吡格雷的早期停止受到影响的影响护理和系统问题。

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