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首页> 外文期刊>Patient Preference and Adherence >Health-Related Quality of Life in Patients with Chronic Kidney Disease in Hemodialysis in Medellín (Colombia)
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Health-Related Quality of Life in Patients with Chronic Kidney Disease in Hemodialysis in Medellín (Colombia)

机译：梅德林血液透析患者血液透析患者的健康状生活质量

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Purpose: Hemodialysis is a treatment that is essential for the survival of patients with terminal chronic kidney disease. However, it is highly invasive, non-curative, and physically, psychologically, socially, and financially demanding, which has an impact on the patient’s health-related quality of life (HRQL). In Colombia, research from the point of view of patients undergoing hemodialysis is scarce. Patients and methods: We conducted a cross-sectional study involving 142 patients undergoing hemodialysis. We used an instrument that included the demographic and clinical information as well as the Charlson Comorbidity Index and Karnofsky Performance Status Scale. HRQL was assessed using EQ-5D-5L and KDQOL-36. The analysis was done using measures of central tendency for quantitative variables and relative frequencies for qualitative variables, in addition bivariate and multivariate regression analyses were conducted. Results: Based on the scores of the EQ-5D-5L scale, it was found that 14.5% subjects showed severe mobility problems, 5.8% were unable to bathe or dress by themselves, 12.9% were unable to perform usual activities, 13.5% were experiencing pain or discomfort (between strong and extreme), and 58.6% showed a certain degree of anxiety or depression. The KDQOL-36 scores were 67.4 ± 19.4 for the symptoms domain and 35.0 ± 27.5 for the disease burden domain. Results of the linear regression analysis showed that the main factors associated with HRQL were the Karnofsky Index and serum albumin levels (p 0.05). Conclusion: The result of this study revealed the impact on the quality of life of Colombian patients undergoing hemodialysis with chronic kidney disease who were highly affected by the disease burden. KDQOL-36 has excellent properties of reliability, internal consistency, and discriminant power; thus, its use is recommended in subsequent studies to monitor HRQL in this population.
机译：目的：血液透析是一种治疗，对患有末端慢性肾病患者的生存至关重要。然而，它是高度侵入性的，非愈合和身体，心理上，社会和财务状况，对患者的健康状生活质量（HRQL）产生影响。在哥伦比亚，从经过血液透析的患者的角度来看，研究是稀缺的。患者及方法：我们进行了涉及血液透析患者的横断面研究。我们使用，其中包括人口和临床信息以及与查尔森合并症指数和卡氏评分量表的仪器。使用EQ-5D-5L和KDQOL-36评估HRQL。通过对定量变量的措施和定性变量的相对频率进行分析，还进行了一致性和多元回归分析。结果：根据EQ-5D-5L规模的分数，发现14.5％的受试者显示出严重的流动性问题，5.8％无法自行沐浴或连衣裙，12.9％无法进行惯常活动，13.5％体验疼痛或不适（在强以之间），58.6％表现出一定程度的焦虑或抑郁症。所述KDQOL-36得分均为症状域67.4±19.4和用于疾病负担域35.0±27.5。线性回归分析的结果表明，与HRQL相关的主要因素是Karnofsky指数和血清白蛋白水平（P <0.05）。结论：本研究的结果揭示了对经受疾病负担影响的慢性肾病经历血液透析患者的生活质量的影响。 KDQOL-36具有优异的可靠性性能，内部一致性和判别力量;因此，在随后的研究中建议使用其使用，以监测该人群中的HRQL。

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