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Clostridium difficile in paediatric populations

机译:Clostridium在儿科群体中艰难梭菌

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An increase in Clostridium difficile infection incidence has been observed among hospitalized children in the United States. The present statement, targeted at clinicians caring for infants and children in community and institutional settings, summarizes the relevant information relating to the role of C difficile in childhood diarrhea and provides recommendations for diagnosis, prevention and treatment. Significant differences between adult and paediatric risk factors and disease are discussed, along with emerging therapies. The relationship between age and disease severity in children with a newly emergent and more fluoroqinolone-resistant strain of C difficile (North American Pulse-field type-1 [NAP1]) remains unknown. The importance of antimicrobial stewardship as a preventive strategy is highlighted. This statement replaces a previous Canadian Paediatric Society position statement on C difficile published in 2000.
机译:在美国住院儿童之间观察到梭菌性艰难梭菌感染率的增加。目前的声明,针对社区和机构环境中的婴儿和儿童的临床医生,总结了与C腹泻腹泻中C艰难岩作用有关的相关信息,并为诊断,预防和治疗提供了建议。讨论了成人和儿科危险因素和疾病之间的显着差异,以及新出现的疗法。患有新出苗和更多氟喹啉抗性菌株C艰难梭菌儿童的年龄和疾病严重程度(北美脉冲场型-1 [NAP1])仍然未知。突出了抗微生物管道的重要性。本声明取代了2000年发布的C Imbericile上的先前加拿大儿科社会陈述。

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