Chromosomal Anomalies Caused by Preovulatory Overripeness of the Primary Oocyte

Yujiroh KAMIGUCHI; Kenji FUNAKI; Kazuya MIKAMO

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Chromosomal Anomalies Caused by Preovulatory Overripeness of the Primary Oocyte

机译：由初级卵母细胞的预保释性高度引起的染色体异常

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Effects of preovulatory overripeness of primary oocytes were studied cytogenetically in 2-cell rat embryos which developed from the ova unduely aged for 48 hours in mature follicles. Both aneuploids and mosaics increased significantly in the experimental group. It was clearly indicated that the delayed ovulation induces nondis j unction and anaphase lag of chromosomes during both the meiotic and first cleavage divisions. A significant increase of polyploidy was also proven as the result of the delay in ovulation. Its causal mechanism was confirmed to be polyspermy.

机译：在2细胞大鼠胚胎中研究了初级卵母细胞的预进入高度影响的影响，该胚胎在成熟卵泡中从OVA产生48小时的OVA开发。在实验组中，一种非动脉和马赛克在显着增加。清楚地表明，在减数分裂和第一次切割划分期间，延迟排卵会诱导染色体的鼻肌滞后。由于排卵延迟的结果，还经过综述增加多倍体。它的因果机制被证实是多患者。

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《Proceedings of the Japan Academy, Series B. Physical and Biological Sciences》 |2006年第8期|共5页
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Yujiroh KAMIGUCHI; Kenji FUNAKI; Kazuya MIKAMO;
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机译：取回后成熟的MI卵母细胞衍生的恒河猴猕猴表现出很高的染色体异常率。
2. Rhesus macaque embryos derived from MI oocytes maturing after retrieval display high rates of chromosomal anomalies [J] . Cathérine Dupont126 Barry D. Bavister24 D. Randall Armant235 and Carol A. Brenner12 Human Reproduction . 2009,第4期

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4. Development of vacuum assisted microfluidic cell trapping device for repositioning of oocyte intracellular chromosomes [C] . Hong Juhee, Purwar Prashant, Lee Sungjoon, IEEE International Conference on Micro Electro Mechanical Systems . 2014

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5. Cytogenetic analyses of bovine preovulatory oocytes. [D] . Kasubick, Susan Frances. 1993

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6. Rhesus macaque embryos derived from MI oocytes maturing after retrieval display high rates of chromosomal anomalies [O] . Cathérine Dupont, Barry D. Bavister, D. Randall Armant, -1

机译：取回后成熟的MI卵母细胞衍生的恒河猴猕猴表现出很高的染色体异常率
7. Rhesus macaque embryos derived from MI oocytes maturing after retrieval display high rates of chromosomal anomalies [O] . Dupont, Cathérine, Bavister, Barry D., Armant, D. Randall, 2008

机译：取回后成熟的MI卵母细胞衍生的恒河猴猕猴表现出很高的染色体异常率

Chromosomal Anomalies Caused by Preovulatory Overripeness of the Primary Oocyte

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