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General Practitioner Use of Generically Substitutable Inhaler Devices and the Impact of Training on Device Mastery and Maintenance of Correct Inhaler Technique

机译:一般从业者使用仿制性吸入器设备以及培训对设备掌握和维护正确吸入技术的影响

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IntroductionGeneric substitution of inhaler devices is a relatively new phenomenon. The best patient outcomes associated with generic substitution occur when prescribers obtain consent from their patients to prescribe a generic inhaler and also teach their patient how to correctly use the new device. To date, no prospective observational study has assessed the level of training required for general practitioners (GPs) to demonstrate correct inhaler technique using two dry powder inhaler devices delivering fixed-dose combination budesonide/formoterol therapy. This study aims to (1) determine the level of training required for GPs to master and maintain correct IT when using two different dry powder inhalers that are able to be substituted in clinical practice and (2) determine the number and types of errors made by GPs on each device and inhaler device preference at each training visit.MethodA randomized, parallel-group cross-over study design was used to compare the inhaler technique of participants with a?Spiromaxsup?/sup placebo device and a Turbuhalersup?/sup placebo device. This study consisted of two visits with each participant over a period of 4?±?1?weeks (visit 1 and visit 2). A total of six levels of assessment and five levels of training were implemented as required. Level 1, no instruction; level 2, following use of written instruction; level 3, following viewing of instructional video; level 4, expert tuition from the researcher; level 5/level 6, repeats of expert tuition from the researcher when required. Participants progressed through each level and stopped at the point at which they demonstrated device mastery. At each level, trained researchers assessed the inhaler technique of the participants. Participants were also surveyed about their previous inhaler use and training.ResultsIn total, 228 GPs participated in this study by demonstrating their ability to use a Turbuhalersup?/sup and a Spiromaxsup?/sup device. There was no significant difference between the proportion of participants who demonstrated device mastery with the Turbuhalersup?/sup compared with the Spiromaxsup?/sup at level 1, (no instruction), (119/228 (52%) versus 131/228 (57%), respectively, n =?228, p =?0.323 (McNemar’s test of paired data). All but one participant had demonstrated correct inhaler technique for both devices by level 3(instructional video). There was a significant difference between the proportion of participants who demonstrated maintenance of device mastery with the Turbuhalersup?/sup compared with the Spiromaxsup?/sup at visit 2, level 1 (127/177 (72%) versus 151/177 (85%) respectively, p =?0.003; McNemar’s test of paired data). All but two participants achieved device mastery by level 3, visit 2. More participants reported previous training with the Turbuhalersup?/sup than with Spiromaxsup?/sup.DiscussionThis study demonstrates that GPs?are able to equally demonstrate correct use of the Turbuhalersup?/sup and Spiromaxsup?/sup devices, even though most had not received training on a Spiromaxsup?/sup device prior to this study. The significance of being able to demonstrate correct technique on these two devices equally has ramifications on practice and supported generic substitution of inhaler devices at the point of prescribing, as the most impactful measure a GP can take to ensure effective use of inhaled medicine is the correct demonstration of inhaler technique.
机译:引入中吸入器的替代是一种相对较新的现象。当公务员从患者获得同意以规定通用吸入器并教授他们的患者如何正确使用新设备时,发生了与通用替代相关的最佳患者结果。迄今为止,未经前瞻性观测研究没有评估一般从业者(GPS)所需的培训水平,用于使用递送固定剂量组合蛋白质/ Formoterol疗法的两种干粉吸入器装置来证明正确的吸入器技术。本研究旨在(1)确定GPS所需的培训水平,并在使用能够在临床实践中取代的两种不同的干粉吸入器,并确定(2)确定所做的错误的数量和类型每个设备上的GPS和吸入器设备偏好每次训练访问。方法随机化,并联组交叉研究设计用于比较参与者的吸入器技术与a?spiromax ?安慰剂装置和涡轮校长?安慰剂设备。本研究由每次参与者的两次访问,在4?±1?周(访问1并访问2)。根据需要共有六个评估和五级培训。 1级,没有指示; 2级,使用书面指示; 3级,查看教学视频之后; 4级,研究人员的专家学费; 5级/ 6级,在需要时,研究人员的专家学费重复。参与者通过每个级别进行,并停止在他们证明设备掌握的那一点。在每个级别,训练有素的研究人员评估了参与者的吸入器技术。参与者也被调查了他们之前的吸入器使用和培训。培训总数,228 GPS通过证明他们使用Turbuhaler 和螺旋形α装置的能力参加了本研究。与Turbuhaler 的参与者的比例与螺旋瘤子β在1级,(没有指令),(没有指令),没有显着差异。(没有指令),(119/228 (52%)与131/228(57%)分别,n =?228,p =?0.323(McNemar对配对数据的测试)。除了3级,一位参与者对两级的设备进行了正确的吸入器技术(教学视频)。与Turbuhaler 在第2级,1级(127 /分别为177(72%)与151/177(85%)分别,p = 0.003; McNemar对配对数据的测试)。除了3级的两位参与者掌握了3级,参观2.更多参与者报告与Turbuhaler的培训报告培训< sup>?与spiromax ? .discussionthis研究表明,GPS?能够同样地证明正确使用Turbuhaler α和spiromax ?设备,即使大多数未接受在本研究之前的spiromax Δ设备上的训练。能够在这两个设备上展示正确技术的重要性同样地具有对实践的影响和支持的通用替代在处方的读者装置,因为GP最具影响力的措施可以采取以确保有效使用吸入药物是正确的吸入技术的演示。

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