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首页> 外文期刊>Ukrainian Biochemical Journal >COVID-19 infection: disease mechanism, vascular dysfunction, immune responses, markers, multiorgan failure, treatments, and vaccination
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COVID-19 infection: disease mechanism, vascular dysfunction, immune responses, markers, multiorgan failure, treatments, and vaccination

机译：Covid-19感染：疾病机制，血管功能障碍，免疫应答，标记，多功能衰竭，治疗和疫苗接种

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The new SARS-CoV-2 virus is a great danger for the worldwide population since there is no known pre-immunity, no specific treatment, and no vaccine. Still, the testing and tracing are the best tools to isolate the infected and prevent the spread of COVID-19. The major goals are to save lives, reduce the mortality rate, increase the survival rate of those are in severe or critical conditions, reduce the hospital stay and accelerate the recovery. This review summarizes the findings on the novel coronavirus that causes COVID-19 and outlines information about symptoms, testing, disease mechanism, vascular dysfunction, immune responses, treatments, and vaccination. At this time no vaccine is available to prevent COVID-19. A literature review reveals that more research is necessary to investigate the interactions between respiratory viruses, human coronaviruses, and the new SARS-CoV-2 virus in the infected population to guide the design of COVID-19 specific therapeutics and vaccines. Almost every government on earth has realized that daily life cannot return to normal until citizens have built up antibodies to safeguard them from the virus. Scientists and manufacturers worldwide are accelerating COVID-19 vaccine research, and pharmaceutical companies are already investing in the large-scale production of vaccines. A synopsis of the most recent sources presented in this review was the starting point for several COVID-19 research projects in the Regional Cooperation for Health, Science and Technology (RECOOP HST) Association managed by Cedars – Sinai Medical Center to gain a better understanding of the COVID-19 disease.
机译：新的SARS-COV-2病毒是全球群体的巨大危险，因为没有已知的急迫，没有特异性治疗，没有疫苗。尽管如此，测试和追踪是隔离感染和防止Covid-19的传播的最佳工具。主要目标是为了挽救生命，降低死亡率，增加人的生存率是严重或严重的条件，减少住院的住宿并加速恢复。本综述总结了新型冠状病毒的研究结果，导致Covid-19并概述有关症状，检测，疾病机制，血管功能障碍，免疫应答，治疗和疫苗接种的信息。此时，没有疫苗可用于预防Covid-19。文献综述表明，需要更多的研究来研究感染人群中呼吸道病毒，人冠状病毒和新SARS-COV-2病毒之间的相互作用，以指导Covid-19特异性治疗和疫苗的设计。几乎所有地球政府都意识到，直到公民建立抗体以保护它们，每日生活无法恢复正常。全球科学家和制造商正在加速Covid-19疫苗研究，制药公司已经投资大规模生产疫苗。本综述中提供的最新来源的概要是雪松 - 西奈医疗中心管理的卫生，科学技术（Recoop HST）协会区域合作中的几个Covid-19研究项目的起点 - 中国医疗中心covid-19疾病。

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