...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Annals of Thoracic Surgery: Official Journal of the Society of Thoracic Surgeons and the Southern Thoracic Surgical Association >Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial
【24h】

Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial

机译：心肌生物标志物在心肌梗死后诊断心肌梗死的准确性，如心脏共振评估：药物，血管成形术，手术研究V（MASS-V）试验

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The lack of a correlation between myocardial?necrosis biomarkers and electrocardiographic abnormalities after revascularization procedures has resulted in a change in the myocardial infarction (MI) definition.MethodsPatients with stable multivessel disease who underwent percutaneous or surgical revascularization were included. Electrocardiograms and concentrations of high-sensitive cardiac troponin I (cTnI) and creatine kinase (CK)-MB were assessed before and after procedures. Cardiac magnetic resonance and late gadolinium enhancement were performed before and after procedures. MI was defined as more than five times the 99th percentile upper reference limit for cTnI and 10 times for CK-MB in percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG), respectively, and new late gadolinium enhancement for cardiac magnetic resonance.ResultsOf the 202 patients studied, 69 (34.1%) underwent on-pump CABG, 67 (33.2%) off-pump CABG, and 66 (32.7%) PCI. The receiver operating characteristic curve showed the accuracy of cTnI for on-pump CABG, off-pump CABG, and PCI patients was 21.7%, 28.3%, and 52.4% and for CK-MB was 72.5%, 81.2%, and 90.5%, respectively. The specificity of cTnI was 3.6%, 9.4%, and 42.1% and of CK-MB was 73.2%, 86.8%, and 96.4%, respectively. Sensitivity of cTnI was 100%, 100%, and 100% and of CK-MB was 69.2%, 64.3%, and 44.4%, respectively. The best cutoff of cTnI for on-pump CABG, off-pump CABG, and PCI was 6.5 ng/mL, 4.5 ng/mL, and 4.5 ng/mL (162.5, 112.5, and 112.5 times the 99th percentile upper reference limit) and of CK-MB was 37.5 ng/mL, 22.5 ng/mL, and 11.5 ng/mL (8.5, 5.1, and 2.6 times the 99th percentile upper reference limit), respectively.ConclusionsCompared with cardiac magnetic resonance, CK-MB was more accurate than cTnI for diagnosing MI. These data suggest a higher troponin cutoff for the diagnosis of procedure-related MI.
机译：心肌梗死程序缺乏心肌梗死生物标志物和心电图异常的相关性导致心肌梗塞（MI）定义的变化。包括经过经皮或外科血管内血管化的稳定多血管疾病的方法。在程序之前和之后评估了心电图和高敏感的心肌肌钙蛋白I（CTNI）和肌酸激酶（CK）-MB的浓度。在程序之前和之后进行心脏磁共振和晚期钆增强。 MI被定义为CTNI的99百分位参考限制的5倍以上，在经皮冠状动脉干预（PCI）和冠状动脉旁路接枝（CABG）中分别为CK-MB的10次，以及心脏磁共振的新晚期钆增强研究了202名患者，研究了69名（34.1％）的泵CABG，67（33.2％）离泵CABG，66（32.7％）PCI。接收器操作特性曲线显示CTNI用于泵车CABG，泵送CABG，PCI患者的精度为21.7％，28.3％和52.4％，CK-MB为72.5％，81.2％和90.5％，分别。 CTNI的特异性为3.6％，9.4％，42.1％，CK-MB分别为73.2％，86.8％和96.4％。 CTNI的敏感性为100％，100％和100％，CK-MB分别为69.2％，64.3％和44.4％。用于泵送CABG，泵送CABG和PCI的CTNI的最佳截止值为6.5ng / ml，4.5 ng / ml和4.5ng / ml（162.5,112.5和99百分位的上参考限制的112.5倍）和分别为37.5ng / ml，22.5ng / ml和11.5ng / ml（8.5,5.1和3.5％的上参考限制2.6倍）。结合心脏磁共振，CK-MB更准确比CTNI用于诊断MI。这些数据表明，用于诊断程序相关的MI的肌钙蛋白截止。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号