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首页> 外文期刊>The journal of Tehran Heart Center. >Relationship between the Severity of Coronary Artery Disease and Catheter-Associated Urethral Stricture in Patients with Acute Coronary Syndrome
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Relationship between the Severity of Coronary Artery Disease and Catheter-Associated Urethral Stricture in Patients with Acute Coronary Syndrome

机译：急性冠状动脉综合征患者冠状动脉疾病和导管相关尿道狭窄严重程度的关系

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Background: Different arterial segments throughout the vascular system develop similar grades of atherosclerosis concomitantly. Urethral ischemia has been proposed as a cause of urethral stricture. Therefore, we aimed to investigate the relationship between coronary artery disease severity using a SYNTAX score and urethral stricture occurrence after urethral catheterization in patients with non–ST-segment-elevation acute coronary syndrome (ACS).Methods: This retrospective study consisted of 306 men with urethral catheters that were diagnosed with ACS and underwent coronary angiography between January 2016 and January 2018 in Kars Kafkas University and Osmaniye Government Hospital, Turkey. Hospital records were reviewed to collect the follow-up data of the patients regarding the occurrence of urethral stricture after urethral catheterization. The study population was divided into 2 groups according to urethral stricture development, and both groups were compared statistically.Results: SYNTAX scores were significantly higher in patients with urethral stricture than in those without urethral stricture (14.86±7.11 vs. 29.25±9.79; P0.001). The SYNTAX score (OR=1.27; 95% CI: 1.16–1.39; P0.001), diabetes, and serum albumin were found to be the independent predictors of urethral stricture. The receiver operating characteristic curve analysis showed that the cutoff value of the SYNTAX score for urethral stricture prediction was greater than 22.5, with 76.7% sensitivity and 85.1% specificity (AUC=0.88, 95% CI: 0.84–0.91; P0.001).Conclusion: Coronary artery disease severity graded according to the SYNTAX score is an independent predictor of urethral stricture occurrence in ACS patients with a urethral catheter inserted.
机译：背景：在整个血管系统中不同的动脉段伴随着伴随着类似的动脉粥样硬化等级。尿道缺血已被提出作为尿道狭窄的原因。因此，我们旨在研究冠状动脉疾病严重性使用尿道癌急性冠状动脉综合征（ACS）尿道导管术后尿道测量和尿道狭窄发生的关系。方法：这个回顾性研究由306名男子组成尿道导管诊断为2016年1月至2018年1月在KARS KAFKAS大学和土耳其奥斯曼伊亚政府医院的ACS和2018年1月的冠状动脉造影。审查了医院记录，收集尿道导管尿道术后尿道狭窄发生的后续数据。根据尿道狭窄的发展，研究人群分为2组，两组统计学比较。结果：尿道狭窄患者的方法显着高于尿道狭窄（14.86±7.11与29.25±9.79; p <0.001）。该语法得分（或= 1.27; 95％CI：1.16-1.39; P <0.001），糖尿病和血清白蛋白被发现是尿道狭窄的独立预测因子。接收机操作特征曲线分析表明，尿道狭窄预测的语法评分的截止值大于22.5，灵敏度为76.7％和85.1％特异性（AUC = 0.88,95％CI：0.84-0.91; P <0.001）。结论：冠状动脉疾病严重程度根据语法评分分级是ACS患者尿道导管的尿道狭窄发生的独立预测因子。

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