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首页> 外文期刊>Thoracic cancer. >Extracranial abscopal effect induced by combining immunotherapy with brain radiotherapy in a patient with lung adenocarcinoma: A case report and literature review
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Extracranial abscopal effect induced by combining immunotherapy with brain radiotherapy in a patient with lung adenocarcinoma: A case report and literature review

机译：用肺腺癌患者组合免疫疗法与脑放射治疗的颅腹噬菌体诱导 - 案例报告与文献综述

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An extracranial abscopal effect induced by brain radiotherapy is particularly unusual because of the brain's distinctive immune microenvironment. We report a case of an extracranial abscopal effect in a 71-year-old male patient with lung adenocarcinoma treated with atezolizumab and later combined with brain radiation for brain metastasis. The subsequent abscopal effect first manifested as pseudoprogression of the primary lesion in the lung before remission was confirmed. This case suggests that immunotherapy increases the chance of an abscopal effect occurring after radiation therapy for brain metastases in patients with primary tumors with low immunogenicity. ? 2019 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.
机译：由于脑的独特免疫微环境，脑放射治疗诱导的颅外横向效应特别不寻常。我们在71岁的男性患者中举报了一种肺腺癌和替代唑珠单抗，后来与脑转移的脑辐射结合的肺腺癌中的颅腺癌中的颅腹骨折效应。随后的横断面效应首次表现为在确认缓解前肺部初级病变的假期突出。这种情况表明，免疫疗法增加了患有低免疫原性肿瘤患者脑转移后发生的横断面效应的可能性。 ？ 2019年的作者。中国肺部肿瘤集团和约翰瓦里和儿子澳大利亚发表的胸癌

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