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首页> 外文期刊>Thoracic cancer. >Feasibility of nodal classification for non‐small cell lung cancer by merging current N categories with the number of involved lymph node stations
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Feasibility of nodal classification for non‐small cell lung cancer by merging current N categories with the number of involved lymph node stations

机译：通过将当前的n个类别与涉及的淋巴结站的数量合并了非小细胞肺癌的节点分类的可行性

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The aim of this study was to assess the prognoses of patients with non-small cell lung cancer (NSCLC) according to the current nodal (N) categories of the tumor, node and metastasis (TNM) classification and the number of involved lymph node stations. Five hundred and seventy patients with NSCLC underwent surgery from 1 January 2005 to 31 December 2009 and were analysed retrospectively. Postoperative overall survival was analysed according to two nodal classifications: the current N0, N1, N2 and N3 categories and those based on the number of involved nodal stations: N0, N1a (single N1), N1b (multiple N1), N2a1 (single N2 without N1), N2a2 (single N2 with N1), N2b1 (multiple N2 without N1) and N2b2 (multiple N2 with N1). Five-year survival rates were 76.1%, 53.4% and 26.3% for N0, N1 and N2, respectively (P 0.001). When survival was analysed by the number of involved nodal stations, the groups with significant differences were maintained; otherwise, they were merged, and new codes were assigned as follows for exploratory analyses: NA (N0), NB (N1a), NC (N1b, N2a (i.e., N2a1 and N2a2) and N2b1) and ND (N2b2). Five-year survival rates were 76.1%, 60.0%, 39.1%, and 11.4% for NA, NB, NC and ND, respectively, and there were significant differences among them. This N classification was an independent prognostic factor in multivariate analyses. Pending prospective and international validation, it is practical to merge the current N categories with the number of involved lymph node stations when evaluating the postoperative prognosis of NSCLC patients. ? 2019 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.
机译：本研究的目的是根据肿瘤，节点和转移（TNM）分类的当前节点（N）类别和涉及淋巴结站的数量来评估非小细胞肺癌（NSCLC）的患者的预期。从2005年1月1日至2009年12月31日开始，七百七十名七十名患有NSCLC接受的手术，并回顾性分析。根据两个节点分类进行分析术后总存活：目前的N0，N1，N2和N3类别以及基于涉及的节点站的数量：N0，N1A（单个N1），N1B（多N1），N2A1（单n2没有N1），N2A2（具有N1的单个N2），N2B1（没有N1的多个N2）和N2B2（具有N1的多个N2）。对于N0，N1和N2，5年生存率为76.1％，53.4％和26.3％（P <0.001）。当通过涉及节奏站的数量分析生存时，维持具有显着差异的群体;否则，它们被合并，并且新的代码分配如下用于探索性分析：Na（N0），Nb（N1A），NC（N1B，N2A（即N2A1和N2A2）和N2B1）和ND（N2B2）。对于NA，NB，NC和ND，5年生存率分别为76.1％，60.0％，39.1％和11.4％，它们之间存在显着差异。该N分类是多变量分析的独立预后因素。待定前瞻性和国际验证，在评估NSCLC患者的术后预后时，将当前的N类合并当前的N类，与涉及的淋巴结站的数量合并。 ？ 2019年的作者。中国肺部肿瘤集团和约翰瓦里和儿子澳大利亚发表的胸癌

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