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ACTH‐producing thymic neuroendocrine tumor initially presenting as psychosis: A case report and literature review

机译:ACTH-产生胸腺神经内分泌肿瘤最初呈现为精神病:案例报告和文献综述

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A 32-year-old woman was referred to our hospital because of severe psychosis and was found to have an ectopic ACTH-producing thymic neuroendocrine tumor. Laboratory data revealed an elevated serum cortisol and plasma ACTH level, hypokalemia, and metabolic alkalosis. Chest computed tomography (CT) revealed an anterior mediastinal mass and multiple pulmonary nodules. As the patient was unable to communicate because of her consciousness disturbance, she was managed with artificial ventilation and deep sedation. Metyrapone and potassium supplementation were administered, and steroid psychosis gradually improved. Thoracic surgery was performed and the histopathological diagnosis was thymic neuroendocrine tumor with positive anti-ACTH immunohistochemical staining. Here we present details of the case and review the literature. ? 2019 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.
机译:一个32岁的女性被称为我们的医院,因为精神病严重,发现有一个异位的胸腺神经内分泌肿瘤。实验室数据揭示了血清皮质醇和血浆acth水平,低钾血症和代谢碱中毒。胸部计算断层扫描(CT)揭示了前纵隔质量和多种肺结节。由于患者由于她的意识障碍而无法沟通,因此她用人工通风和深镇静进行了管理。弥补符合梅罗布松和钾补充剂,类固醇精神病逐渐改善。进行胸部手术,组织病理学诊断是胸腺神经内分泌肿瘤,具有正抗ACTH免疫组化染色。在这里,我们展示了案件的详细信息并审查文献。 ? 2019年的作者。中国肺部肿瘤集团和约翰瓦里和儿子澳大利亚发表的胸癌

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