...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Therapeutic advances in drug safety. >Continuation of atypical antipsychotic medications in critically ill patients discharged from the hospital: a single-center retrospective analysis
【24h】

Continuation of atypical antipsychotic medications in critically ill patients discharged from the hospital: a single-center retrospective analysis

机译：从医院排出的危重病患者中的非典型抗精神病药的延续：单中心回顾性分析

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Atypical antipsychotics (AAP) have been associated with reduced duration of delirium in the intensive care setting. However, long-term use of these drugs is associated with significant adverse events, including increased all-cause mortality in the elderly. Inappropriate continuation of AAPs after discharge from the intensive care unit (ICU) is worrisome and needs to be addressed.The aim of this work was to assess the prevalence of continuation of AAPs after hospital discharge and evaluate the associated risk factors. This was a single-center retrospective chart analysis in the setting of adult ICUs at a tertiary care academic medical center. It involved all adult patients admitted to the ICU and initiated on AAPs from January 2012 to December 2014. The measurements were: (1) prevalence of ICU-initiated AAP continuation following hospital discharge, (2) risk factors associated with continuation of AAPs following hospital discharge, and (3) risk of continuation of AAPs in patients ?65 years of age. A total of 55% of ICU patients initiated on AAPs were discharged from the hospital with a prescription for continued AAP therapy. Male sex and discharge location were highly associated with continuation upon discharge. Older patients (?65 years of age) were not at a higher risk of being continued on these drugs after discharge. Male sex and discharge to a healthcare facility were associated with a higher rate of continuation. Research into practical methods to reduce their continuation upon discharge should be performed to mitigate the long-term risks of AAP administration.
机译：非典型抗精神病药（AAP）已与重症监护环境中的谵妄持续时间减少有关。然而，这些药物的长期使用与显着不良事件有关，包括增加老年人的所有导致死亡率。从重症监护室（ICU）出院后不适当的AAP延续令人担忧，需要解决。这项工作的目的是评估医院排放后延续AAP的普遍存在，并评估相关的危险因素。这是在第三级护理学术医疗中心的成人ICU设置中的单中心回顾表分析。它涉及所有成年患者录取ICU，并于2012年1月开始AAP到2014年12月。测量结果：（1）ICU启动的AAP持续延续，后院出院后，（2）与延续医院延续的危险因素放电，（3）患者延续AAP的风险？65岁。共有55％的ICU患者在AAP中发起的患者从医院排出，处方于持续的AAP治疗。男性性和放电位置与放电时的延续高度相关。在出院后，年龄较大的患者（65岁）的风险较高。男性性和向医疗保健设施排放与较高的延续速度相关。应进行实际方法，以减少出院后继续的方法，以减轻AAP管理的长期风险。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号