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Adverse drug reactions reporting in Turkey and barriers: an urgent need for pharmacovigilance education

机译:土耳其和壁垒报告的不良药物反应:迫切需要药剂统治教育

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The World Health Organization (WHO) has defined adverse drug reaction (ADR) as “a noxious, accidental and undesirable outcome of the drug at a normal therapeutic dose”.1 ADRs are very common throughout the globe and are responsible for increased hospitalization and even mortality.2 In addition, ADRs also increase the length of stay and cost of treatment.1,3 An effective evaluation and medication surveillance mechanism is crucial for the prevention of ADRs.3,4 Pharmacovigilance, which involves the identification of responsible causes, recognition, recording, monitoring and taking measures against a problem encountered in drug administration, is a known evaluation mechanism.5 The main reasons behind ADRs happening are polypharmacy, off-label drug usage, patients with comorbidities, and individual variations in genetic makeup.
机译:世界卫生组织(世卫组织)将不良药物(ADR)定义为“在正常治疗剂量的药物中的一种有害,意外和不良和药物的不良结果”.1 ADRS在全球范围内非常普遍,并负责增加住院治疗甚至2.此外,ADR还增加了保持时间和治疗成本.1,3有效的评估和药物监测机制对于预防ADRS.3,4药物知识至关重要,这涉及识别负责任的原因,认可,录制,监测和采取措施对药物管理局遇到的问题,是一种已知的评估机制.5 ADRS发生后面的主要原因是复数,缺斑药物使用,患者,具有遗传构成的单独变化。

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