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首页> 外文期刊>Therapeutic advances in endocrinology and metabolism. >Association between air pollution and type 2 diabetes: an updated review of the literature
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Association between air pollution and type 2 diabetes: an updated review of the literature

机译：空气污染与2型糖尿病之间的关联：对文献的更新审查

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Air pollution and type 2 diabetes mellitus (T2DM) are critical public health issues worldwide. A large number of epidemiological studies have highlighted the adverse effects of air pollution on diabetes, and include risk profiles for different exposure durations, study design types, subgroup populations, and effects of air pollution components. We researched PubMed, Google Scholar, and Web of Science to identify studies on the association between air pollution and T2DM from January 2009 to January 2019. The aim of this review is to provide a brief overview of epidemiological and experimental studies on air pollution associated with T2DM from the latest research, which may provide practical information about this relationship and possible mechanisms. Current cumulative evidence appears to suggest that T2DM-related biomarkers increase with increasing exposure duration and concentration of air pollutants. The chemical constituents of the air pollutant mixture may affect T2DM to varying degrees. The suggested mechanisms whereby air pollutants induce T2DM include increased inflammation, oxidative stress, and endoplasmic reticulum stress.
机译：空气污染和2型糖尿病（T2DM）是全世界关键的公共卫生问题。大量流行病学研究突出了空气污染对糖尿病的不利影响，包括不同曝光持续时间，研究设计类型，亚群群体的风险曲线，以及空气污染成分的影响。我们研究了PubMed，Google Scholar和科学网络，以确定2009年1月至2019年1月的空气污染和T2DM之间的研究。本综述的目的是简要概述关于与之相关的空气污染的流行病学和实验研究T2DM来自最新研究，可以提供有关这种关系的实用信息和可能的机制。目前的累积证据似乎表明T2DM相关的生物标志物随着曝光持续时间和空气污染物的浓度而增加。空气污染物混合物的化学成分可能影响T2DM到不同程度。空气污染物诱导T2DM的建议机制包括增加的炎症，氧化应激和内质子ressulum rentulum。

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