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首页> 外文期刊>Toxicology Reports >Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometry
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Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometry

机译：用超高效液相色谱法评价胶囊和法国压咖啡中的雌激素化学物质用串联质谱法

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The objective of this study was to examine exposure to estrogenic chemicals (ECs) via capsule coffee. Twenty-two brands of capsule coffee and 15 brands of French press coffee for comparison were brewed, and their contents of ECs were identified and quantified using ultra-performance liquid chromatography with tandem mass spectrometry. Exposure to ECs in coffee were compared to tolerable daily intake guidelines to assess potential hazard to health. Benzophenone was the most frequently detected EC in capsule coffee (mean concentration?±?SD: 20.37?±?47.07?ng/mL, n?=?6), followed by bisphenol A (BPA, 0.31?±?0.71, n?=?4), dibutyl phthalate (1.41?±?3.58, n?=?3), 4-nonylphenol (0.67?±?1.82, n?=?3) and bisphenol F (BPF, 0.49?±?1.54, n?=?2). BPA and BPF were each detected in 3 French press coffee samples (0.29?±?0.58 and 0.85?±?1.75?ng/mL, respectively). Two French press coffee brands purchased as ground coffee rather than whole bean were positive for ECs (BPA in one and BPF in both). Hazard indexes were below 1.0 for each EC for both coffee types. These results indicate that there is EC contamination in capsule and French press coffee, but the quantities of ECs are low relative to established safety guidelines.
机译：本研究的目的是通过胶囊咖啡检查暴露于雌激素化学品（ECS）。 22个品牌的胶囊咖啡和15个品牌的法国压咖啡进行了比较，并使用具有串联质谱法的超高效液相色谱法鉴定和定量ECS的内容。将与ECS暴露在咖啡中进行比较，以抵押日常摄入指南，以评估对健康的潜在危害。二苯甲酮是胶囊咖啡中最常检测到的EC（平均浓度？±sd：20.37？±47.07？ng / ml，n？=Δ6），然后是双酚A（BPA，0.31？±0.71，N？ =Δ4），邻苯二甲酸二丁酯（1.41≤α±3.58，N？= 3），4-壬基酚（0.67？±1.82，N？=β3）和双酚F（BPF，0.49？±？1.54，N ？=？2）。每次检测到BPA和BPF，分别检测到3种法国压榨咖啡样品（0.29≤x≤0.58和0.85？±1.75？Ng / ml）。两种法国新闻咖啡品牌购买的咖啡咖啡而不是全豆对ECS阳性（BPA在一个和BPF中）。对于两种咖啡类型的每个EC，危险索引低于1.0。这些结果表明，胶囊和法式压咖啡中存在EC污染，但相对于既定的安全指南，ECS的数量低。

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