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首页> 外文期刊>Data in Brief >Molecular characterization and gene expression data of liver expressed antimicrobial Peptide-2 (LEAP-2) isolated from rock bream ( Oplegnathus fasciatus)
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Molecular characterization and gene expression data of liver expressed antimicrobial Peptide-2 (LEAP-2) isolated from rock bream ( Oplegnathus fasciatus)

机译:肝脏表达抗菌肽肽-2(Leap-2)的分子表征和基因表达数据从岩鲷分离( oplegnathus fasciatus fasciatus

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Antimicrobial peptides (AMPs) are known to play a role as a first line of defence against microbial invasion. Liver Expressed Antimicrobial Peptides-2 (LEAP-2) is one of the AMPs. LEAP-2 includes four highly conserved cysteine residues and belongs to a cysteine-rich peptides group. We identified and characterized the molecular properties of LEAP-2 in rock bream. The expression levels of rock bream LEAP-2 (RbLEAP-2) in the 12 different tissues of healthy fish?and the RbLEAP-2 expression pattern after infections withEdwardsiella piscicida(E. piscicida),Streptococcus iniae(S. iniae) and red seabream iridovirus (RSIV) were examined. This data provide that RbLEAP-2 plays an important role in innate immunity when rock bream is infected with a pathogen.
机译:已知抗微生物肽(AMPS)作为针对微生物侵袭的第一线路的作用发挥作用。肝脏表达抗微生物肽-2(LEAP-2)是AMPS之一。 LEAP-2包括四个高度保守的半胱氨酸残基,属于富含半胱氨酸的肽基团。我们鉴定并表征了岩石鲷的Leap-2的分子特性。在健康鱼的12种不同组织中岩石鲷-2(RBLEAP-2)的表达水平?和RBLEAP-2表达模式在感染后,感染氏菌氏菌(e。PISCICIDA),链球菌INIAE(INIE)和RED Seabream检查了Irovovirus(RSIV)。当岩鲷感染病原体时,这种数据提供了RBLEAP-2在先天免疫中起重要作用。

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