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首页> 外文期刊>Degenerative Neurological and Neuromuscular Disease >Alzheimer’s Disease – Why We Need Early Diagnosis
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Alzheimer’s Disease – Why We Need Early Diagnosis

机译：阿尔茨海默病 - 为什么我们需要早期诊断

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Alzheimer’s disease is the leading cause of dementia. However, neither Alzheimer’s disease nor Alzheimer’s dementia are an inevitable consequence of aging. This review provides an overview of the issues involved in a diagnosis of Alzheimer’s disease before an individual meets the criteria for Alzheimer’s dementia. It examines how Alzheimer’s disease diagnosis rates can be improved, the implications of an early diagnosis for the individual, carer and society, and the importance of risk reduction to prevent or delay progression. Although no disease-modifying agents capable of reversing the initial pathological changes are currently available, it may be possible to prevent or delay the development of dementia in a proportion of the population by modifying exposure to common risk factors. In other individuals, diagnosing the disease or risk of disease early is still valuable so that the individual and their carers have time to make choices and plan for the future, and to allow access to treatments that can help manage symptoms. Primary healthcare professionals play a pivotal role in recognising individuals at risk, recommending lifestyle changes in mid-adult life that can prevent or slow down the disease, and in timely diagnosis. Early intervention is the optimal strategy, because the patient’s level of function is preserved for longer.
机译：阿尔茨海默病是痴呆症的主要原因。然而，Alzheimer的疾病和阿尔茨海默痴呆症都不是老龄化的必然结果。本综述概述了在个人符合阿尔茨海默痴呆症的标准之前涉及阿尔茨海默病的诊断问题。它研究了阿尔茨海默氏症的疾病诊断率如何提高，对个人，护理人员和社会的早期诊断的影响以及风险降低的重要性，以防止或延迟进展。尽管目前没有能够逆转初始病理变化的疾病改性剂，但是可以通过改变暴露于普通风险因素，预防或延迟痴呆症的发展。在其他人中，诊断疾病或疾病的风险早期仍然有价值，因此个人和他们的护理人员有时间为未来做出选择和计划，并允许获得可以帮助管理症状的治疗方法。主要医疗保健专业人员在识别危险的个人方面发挥关键作用，建议生活方式在中成人生活中的变化，可以预防或缓慢疾病，及时诊断。早期干预是最佳的策略，因为患者的功能水平被保留更长。

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