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首页> 外文期刊>Dental Materials Journal >Activation of matrix-bound endogenous proteases by self-etch adhesives
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Activation of matrix-bound endogenous proteases by self-etch adhesives

机译：通过自蚀刻粘合剂激活基质结合的内源蛋白酶

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摘要

The study evaluated changes in total enzymatic activity and degradation of demineralized dentin following the application of universal or self-etch adhesives. The universal adhesives —Scotchbond Universal (SU) and All-Bond Universal (ABU) and self-etch adhesives —Adper Easy Bond (EB) and G-aenial Bond (GB) were used for 2 min pretreatment of the dentin beams. Phosphoric acid (PA) treatment as well as no treatment served as controls. Total enzymatic activity was analyzed before and after treatment, collagen degradation was assessed using mass loss, C-terminal telopeptide (CTX) and C-terminal-telopeptide of type I collagen (ICTP) release (24 h, 3-day, 3-week). Over three weeks of incubation, ICTP release of ABU treated beams was significantly higher than other groups (p <0.05), except for SU treated beams (p >0.05) and CTX release of GB treated beams was the highest among the groups with statistically significant difference (p <0.05). The results confirm that the universal adhesives tested have also potential to increase the enzymatic activity in dentin.
机译：该研究评估了通用或自蚀刻粘合剂之后酶促活性的总酶活性和降解的脱矿化牙本质的变化。通用粘合剂 - Scotchong网上通用（SU）和全粘合通用（ABU）和自蚀刻粘合剂 - Asy Easy Bond（EB）和G-Aenial键（GB）用于牙本质束的2分钟预处理。磷酸（PA）处理以及无需治疗作为对照。在处理之前和之后分析总酶活性，使用I型胶原蛋白（ICTP）释放的质量损失，C末端腹膜（CTX）和C-末端肽（24小时，3天，3周）评估胶原蛋白降解）。在孵化三周内，ABU处理梁的ICTP释放显着高于其他组（ P <0.05），除了SU处理的光束（ p> 0.05），GB处理的光束的CTX释放是最高的在具有统计学上显着差异的群体中（ P <0.05）。结果证实，测试的通用粘合剂也有可能增加牙本质中的酶活性。

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